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Histologic Basis of Vessel Remodeling after Various Interventional Procedures: A Comparison of Acute (Cracks, Breaks, Tears, Stretching) and Chronic (Tissue Proliferation, Recoil) Changes

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Arterial Remodeling: A Critical Factor in Restenosis

Part of the book series: Developments in Cardiovascular Medicine ((DICM,volume 198))

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Abstract

During the past two decades, there has been an explosive increase in the number of techniques and devices used to treat obstructed coronary arteries. Since its introduction in 1977 (1), catheter balloon angioplasty has gained wide acceptance as a nonsurgical form of therapy for acutely and chronically obstructed coronary arteries, and this technique forms the centerpiece around which newer tools and techniques have been developed. Of the many interventional devices currently used or under study, their morphologic effects (“remodeling”) on vessel luminal shape or obstruction can be separated into two underlying processes (2): (a) remodeling (“displacing,” “expanding,” “attaching”) and (b) removing (“heating,” “drilling,” “excising”) (Tables 1, 2). This chapter will review acute and chronic changes of remodeling after balloon angioplasty and other interventional techniques.

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Authors and Affiliations

  1. The Cardiovascular Pathology Registry, St. Vincent Hospital, Indianapolis, Indiana, USA

    Bruce F. Waller

  2. Nasser, Smith & Pinkerton Cardiology, Inc., Indianapolis, Indiana, USA

    Bruce F. Waller, Charles M. Orr, James Van Tassel, Thomas Peters, Edward Fry & James Hermiller

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  1. Bruce F. Waller
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  2. Charles M. Orr
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  3. James Van Tassel
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  4. Thomas Peters
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  5. Edward Fry
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  6. James Hermiller
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Editors and Affiliations

  1. Necker University, Paris, France

    Antoine Lafont

  2. Cleveland Clinic Foundation, Cleveland, Ohio, USA

    Eric J. Topol

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Waller, B.F., Orr, C.M., Van Tassel, J., Peters, T., Fry, E., Hermiller, J. (1997). Histologic Basis of Vessel Remodeling after Various Interventional Procedures: A Comparison of Acute (Cracks, Breaks, Tears, Stretching) and Chronic (Tissue Proliferation, Recoil) Changes. In: Lafont, A., Topol, E.J. (eds) Arterial Remodeling: A Critical Factor in Restenosis. Developments in Cardiovascular Medicine, vol 198. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-6079-1_6

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  • DOI: https://doi.org/10.1007/978-1-4615-6079-1_6

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