Abstract
Understanding the mechanisms that produce and the development of effective treatments for restenosis following angioplasty have eluded intense efforts over two decades. Enthusiasms for various therapies have waxed and waned, confronting us with the limitations of our mastery of the biology of restenosis. Our initial concepts of the mechanisms of restenosis now appear naive. Although we have learned a great deal from animal models of arterial injury, direct translation of the findings of such studies to the more complex situation in humans has proven frustrating.
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Libby, P. et al. (1997). Inflammatory Mechanisms of Remodeling in Injured Arteries. In: Lafont, A., Topol, E.J. (eds) Arterial Remodeling: A Critical Factor in Restenosis. Developments in Cardiovascular Medicine, vol 198. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-6079-1_21
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DOI: https://doi.org/10.1007/978-1-4615-6079-1_21
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