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Molecular Biology of Mycobacterium Tuberculosis

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Mycobacteria

Abstract

Molecular biology is simply the study of the biology of organisms at the molecular level. It includes investigations to define cellular architecture, biochemical pathways, macromolecular composition, structure, and function, and gene structure, regulation, and expression. This broad discipline of science encompasses diverse techniques ranging from sophisticated chemistry such as mass spectros-copy and x-ray crystallography to simple biochemistry such as assays for β-galactosidase activity. This chapter will concentrate on the aspect of molecular biology usually referred to as molecular genetics, which is concerned with defining gene structure, regulation of gene expression, protein products of genes, and functions of genes and gene products. The reader is referred to other chapters in this volume and several recent excellent reviews for discussions of other aspects of the molecular biology of Mycobacterium tuberculosis, including cellular architecture, macromolecular composition, and biochemistry (1–3).

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  1. University of Illinois at Chicago College of Medicine, Chicago, Illinois

    Pattisapu R. J. Gangadharam PH.D. (Professor of Medicine, Microbiology, and Pathology Director of Mycobacteriology Research) (Professor of Medicine, Microbiology, and Pathology Director of Mycobacteriology Research)

  2. Public Health Laboratory Service, University Hospital of Wales, UK

    P. Anthony Jenkins PH.D. (formerly Director) (formerly Director)

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© 1998 Springer Science+Business Media Dordrecht

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Shinnick, T.M. (1998). Molecular Biology of Mycobacterium Tuberculosis . In: Gangadharam, P.R.J., Jenkins, P.A. (eds) Mycobacteria. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-5987-0_3

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  • DOI: https://doi.org/10.1007/978-1-4615-5987-0_3

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-7743-6

  • Online ISBN: 978-1-4615-5987-0

  • eBook Packages: Springer Book Archive

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