Abstract
Control of the balance between the life and death of cells is crucial to the proper development of tissues and organs. The proliferation of cells is highly orchestrated with a complexity of molecular checks and balances, but a cell that will not stop dividing presents problems as it can become a tumor. In contrast, a genetically programmed cell death mechanism, apoptosis, regulates cell numbers and is a means whereby unwanted or potentially harmful cells are eliminated. Accurate control of cellular life and death involves a plethora of molecular signals and switches, and an essential aspect is how these are activated and terminated at precisely the correct moment.1
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Burdon, R.H. (1997). Oxyradicals as Signal Transducers. In: Forman, H.J., Cadenas, E. (eds) Oxidative Stress and Signal Transduction. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-5981-8_13
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