Abstract
Most myelin-forming and non-myelin-forming Schwann cells of peripheral nerves develop from the neural crest (Anderson, 1993; Bronner-Fraser, 1993; Jessen and Mirsky, 1992; Le Douarin et al., 1991; Marusich and Weston, 1991). The other main glial types in the peripheral nervous system (PNS), are also thought to be derived from the crest. This includes the teloglia associated with somatic motor terminals, satellite cells associated with neuronal cell bodies in sensory, sympathetic and parasympathetic ganglia and the enteric glial cells in the intrinsic ganglia of the gut (Georgiou et al., 1994; Gershon et al., 1993; Pannese, 1981). There is evidence that some of the PNS glia found in nerves/ganglia close to the central nervous system (CNS) are not derived from neural crest cells. Thus, some of the Schwann cells in the ventral roots of the spinal cord arise from ventral neural tube and, some satellite and/or Schwann cells of dorsal root ganglia (DRG) are likely to originate from neuroepithelial cells in the spinal cord after migration of the neural crest is complete (Carpenter and Hollyday, 1992; Loring and Erickson, 1987; Lunn et al., 1987; Rickman et al., 1985; Sharma et al., 1995).
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Jessen, K.R., Mirsky, R., Dong, Z., Brennan, A. (1997). Developmental Regulation of Schwann Cell Precursors and Schwann Cell Generation. In: Juurlink, B.H.J., Devon, R.M., Doucette, J.R., Nazarali, A.J., Schreyer, D.J., Verge, V.M.K. (eds) Cell Biology and Pathology of Myelin. Altschul Symposia Series, vol 4. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-5949-8_17
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