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Advances in Cirrhosis, Hyperammonemia, and Hepatic Encephalopathy pp 173–183Cite as

Hyperammonaemia without Portal Systemic Shunting Does Not Resemble Hepatic Encephalopathy

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Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 420))

Abstract

During our experimental studies on the role of ammonia in the pathogenesis of hepatic encephalopathyl we did the interesting observation: a 20 times increased blood ammonia concentration caused no symptoms of encephalopathy in SHAM-operated rats, but it did definitely in portacaval shunted (PCS) rats.

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Authors and Affiliations

  1. Laboratory of Experimental Internal Medicine Academic Medical Center, University of Amsterdam, The Netherlands

    Robert A. F. M. Chamuleau & Birgit A. P. M. Vogels

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  1. Robert A. F. M. Chamuleau
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  2. Birgit A. P. M. Vogels
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Editors and Affiliations

  1. Instituto de Investigaciones Citologicas de la F. V. I. B., Valencia, Spain

    Vicente Felipo  & Santiago Grisolía  & 

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Chamuleau, R.A.F.M., Vogels, B.A.P.M. (1997). Hyperammonaemia without Portal Systemic Shunting Does Not Resemble Hepatic Encephalopathy. In: Felipo, V., Grisolía, S. (eds) Advances in Cirrhosis, Hyperammonemia, and Hepatic Encephalopathy. Advances in Experimental Medicine and Biology, vol 420. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-5945-0_11

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  • DOI: https://doi.org/10.1007/978-1-4615-5945-0_11

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-7724-5

  • Online ISBN: 978-1-4615-5945-0

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