Abstract
We are interested in the physiological roles of the sialoglycoconjugates associated with rod photoreceptor cells, which specifically metabolize sialic acids by balancing sialyltransferase with sialidase (1, 2). Defects of O- and N-linked sialoglycoconjugates may cause retinal dysplasia and retinal degeneration, respectively, in humans (3). Retinal degeneration can be experimentally induced in rats by modification of sialic acids of retinal sialoglycoconjugates (4, 5), but the pathomechanism underlying this degenerative process remains to be clarified.
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Uehara, F. et al. (1997). Glycohistochemical Study of Light-Induced Retinal Degeneration. In: LaVail, M.M., Hollyfield, J.G., Anderson, R.E. (eds) Degenerative Retinal Diseases. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-5933-7_21
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DOI: https://doi.org/10.1007/978-1-4615-5933-7_21
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