Abstract
Seminoma cells, like intratubular tumor cells (carcinoma in situ), are characterized by abundant cytoplasmic glycogen. Visualization of glycogen in histologic sections has been shown to be a valuable diagnostic tool for detecting tumor cells in testicular tissue provided that appropriate fixatives were used to preserve the glycogen in the cells. Tumor cells fixed with 5.5 % glutaraldehyde show virtually no loss of their highly soluble content. In combination with other structural characteristics even single tumor cells can be histologically diagnosed (Holstein et al., 1987).
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© 1997 Springer Science+Business Media New York
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Lauke, H. (1997). Rapid Method to Detect CIS-Cells. In: Ivell, R., Holstein, AF. (eds) The Fate of the Male Germ Cell. Advances in Experimental Medicine and Biology, vol 424. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-5913-9_11
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DOI: https://doi.org/10.1007/978-1-4615-5913-9_11
Publisher Name: Springer, Boston, MA
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