Abstract
The increased sensitivity of the carotid bodies (CB) of different animals and humans to hypoxia is a well documented mechanism contributing to ventilatory acclimatization to hypoxia. The goat CB is special in that it increases its sensitivity to hypoxia in merely 4 h (Bisgard, 1994), which is compared with that of the rat, cat or humans which need longer periods of hypoxia to reach the peak of their increased sensitivity to hypoxia. The underlying mechanisms accounting for increased CB sensitivity to hypoxia is unknown. The objectives of this study were to define the morphology of the goat CB and to determine if structural changes could be detected associated with a change in the hypoxic sensitivity of the goat CB.
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Xue, D., Keith, I.M., Dwinell, M.R., Bisgard, G.E. (1996). Mitochondrial Division, Blood Vessel Dilation, and Large Intercellular Space Expansion of Goat Carotid Body During Hypoxia. In: Zapata, P., Eyzaguirre, C., Torrance, R.W. (eds) Frontiers in Arterial Chemoreception. Advances in Experimental Medicine and Biology, vol 410. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-5891-0_6
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DOI: https://doi.org/10.1007/978-1-4615-5891-0_6
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