Abstract
Ventilatory acclimatization to hypoxia (VAH) is the time-dependent increase in ventilation that occurs in mammals (including humans) during prolonged exposure to hypoxic environments. Goats acclimatize rapidly, reaching a ventilatory plateau within 4–6 hours of breathing hypoxic gas (Engwall & Bisgard, 1990). Evidence strongly suggests that VAH is caused by a time-dependent increase in carotid body (CB) sensitivity to hypoxia in goats (Nielsen et al, 1988). However, the mechanism for increased CB hypoxic sensitivity remains unknown.
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© 1996 Springer Science+Business Media New York
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Janssen, P.L., Dwinell, M.R., Pizarro, J., Bisgard, G.E. (1996). Effects of Continuous Intracarotid Infusion of Dopamine During Long-Term Hypoxia in Awake Goats. In: Zapata, P., Eyzaguirre, C., Torrance, R.W. (eds) Frontiers in Arterial Chemoreception. Advances in Experimental Medicine and Biology, vol 410. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-5891-0_59
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DOI: https://doi.org/10.1007/978-1-4615-5891-0_59
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