Skip to main content

Localization of Nicotinic Acetylcholine Receptors in Cat Carotid Body and Petrosal Ganglion

  • Chapter
Frontiers in Arterial Chemoreception

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 410))

Abstract

How the carotid body converts hypoxic stimuli into neural activity remains largely unknown. Several neurotransmitters, which have been demonstrated in type I cells in the carotid body, are still candidates for primary neurotransmitter(s) of chemotransduction.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Brewer GJ, Torricelli JR, Evege EK & Price PJ (1993) Optimized survival of hippocampal neurons in B27-supple-mented Neurobasal, a new serum-free medium combination. J Neurosci Res 35: 567–576

    Article  PubMed  CAS  Google Scholar 

  • Chen IL & Yates RD (1984) Two types of glomus cell in the rat carotid body as revealed by α-bungarotoxin binding. J Neurocytol 13: 281–302

    Article  PubMed  CAS  Google Scholar 

  • Conroy WG & Berg DK (1995) Neurons can maintain multiple classes of nicotinic acetylcholine receptors distinguished by different subunit compositions. J Biochem Mol Biol 270: 4424–4431

    CAS  Google Scholar 

  • Dinger B, González C, Yoshizaki K & Fidone S (1981) Alpha-bungarotoxin binding in cat carotid body. Brain Res 205:187–193

    Article  PubMed  CAS  Google Scholar 

  • Dinger BG, Hirano T & Fidone SJ (1986) Autoradiographic localization of muscarinic receptors in rabbit carotid body. Brain Res 367: 328–331

    Article  PubMed  CAS  Google Scholar 

  • Fitzgerald RS & Shirahata M (1994) Acetylcholine and carotid body excitation during hypoxia an the cat. J Appl Physiol 76: 1566–1574

    PubMed  CAS  Google Scholar 

  • Fitzgerald RS, Shirahata M & Ide T (1996) Further cholinergic aspects of carotid body chemotransduction of hypoxia in the cat. J Appl Physiol (In press)

    Google Scholar 

  • Ishizawa Y, Schofield B, Chou CL & Shirahata M (1995) Changes in protein expression of cultured cat glomus cells. ISOTT95 Satellite Symposium: Adaptation to Hypoxia. IV.3

    Google Scholar 

  • Klimaschewski L, Reuss S, Spessert R, Lobron C, Wevers A, Heym C, Maelicke A & Schröder H (1994) Expression of nicotinic acetylcholine receptors in the rat superior cervical ganglion mRNA and protein level. Mol Brain Res 27: 167–173

    Article  PubMed  CAS  Google Scholar 

  • McGehee DS & Role LW (1995) Physiological diversity of nicotinic acetylcholine receptors expressed by vertebrate neurons. Annu Rev Physiol 57: 521–546

    Article  PubMed  CAS  Google Scholar 

  • McGehee DS, Heath MJ, Gelber S, Devay P & Role LW (1995) Nicotinic enhancement of fast excitatory synaptic transmission in CNS by presynaptic receptors. Science 269: 1692–1696

    Article  PubMed  CAS  Google Scholar 

  • Rogers SW, Mandelzys A, Deneris ES, Cooper E & Heinemann S (1992) The expression of nicotinic acetylcholine receptors by PC12 cells treated with NGF. J Neurosci 12: 4611–4623

    PubMed  CAS  Google Scholar 

  • Shirahata M, Schofield B, Chin BY & Guilarte TR (1994) Culture of arterial chemoreceptor cells from adult cats in defined medium. Brain Res 658: 60–66

    Article  PubMed  CAS  Google Scholar 

  • Zhang X, Gong Z-H, Hellström-Lindahl E & Nordberg A (1995) Regulation of ±4 β2 nicotinic acetylcholine receptors in M10 cells following treatment with nicotinic agents. NeuroReport 6: 313–317

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1996 Springer Science+Business Media New York

About this chapter

Cite this chapter

Ishizawa, Y., Fitzgerald, R.S., Shirahata, M., Schofield, B. (1996). Localization of Nicotinic Acetylcholine Receptors in Cat Carotid Body and Petrosal Ganglion. In: Zapata, P., Eyzaguirre, C., Torrance, R.W. (eds) Frontiers in Arterial Chemoreception. Advances in Experimental Medicine and Biology, vol 410. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-5891-0_37

Download citation

  • DOI: https://doi.org/10.1007/978-1-4615-5891-0_37

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-7702-3

  • Online ISBN: 978-1-4615-5891-0

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics