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Exercise Tolerance and Impairment of Sympathetic Nervous System Activity

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The Physiology and Pathophysiology of Exercise Tolerance

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Abstract

The activity of the peripheral sympathetic nervous system can be evaluated based on its influence on the organism as a whole; in terms, for example, of the blood pressure and heart rate responses. Because of the complex regulation of these variables, however, such an approach remains problematic. The evaluation of sympathetic activity can be more reliably based on an analysis of plasma and urinary catecholamine profiles (17-19,31,35). This approach is justified on the basis of correlations that have been demonstrated (i) between the heart rate responses to sympathetic stimulation and the release of endogenous catecholamines into the coronary sinus of the dog (40), and (ii) between sympathetic activity in sympathetic fibers of peripheral nerves, recorded with microelectrodes, and the venous noradrenaline concentration of the respective extremity (38).

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Author information

Authors and Affiliations

  1. Department of Sports and Performance Medicine, Medical University Hospital Ulm, D-89075, Ulm, Germany

    Manfred J. Lehmann & Uwe Gastmann

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  1. Manfred J. Lehmann
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  2. Uwe Gastmann
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Editors and Affiliations

  1. University of Ulm, Ulm, Germany

    Jürgen M. Steinacker

  2. South Bank University, London, England

    Susan A. Ward

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© 1996 Springer Science+Business Media New York

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Lehmann, M.J., Gastmann, U. (1996). Exercise Tolerance and Impairment of Sympathetic Nervous System Activity. In: Steinacker, J.M., Ward, S.A. (eds) The Physiology and Pathophysiology of Exercise Tolerance. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-5887-3_26

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  • DOI: https://doi.org/10.1007/978-1-4615-5887-3_26

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