Activation of Thrombocytes and the Hemostatic System During Maximal Cycle Exercise in Healthy Triathletes

  • Martin Möckel
  • Natalie-Viviane Ulrich
  • Lothar Röcker
  • Andreas Ruf
  • Frank Klefisch
  • Oliver Danne
  • Jörn Vollert
  • Reinhold Müller
  • Thomas Bodemann
  • Heinrich Patscheke
  • Hermann Eichstädt
  • Thomas Störk
  • Ulrich Frei


Physical exercise is widely regarded to be important for health. However, heavy physical exertion has been shown to be associated with a higher incidence of myocardial infarction (3, 13, 30). It has also been shown that physical exercise activates fibrinolysis, coagulation and thrombocytes (8, 9, 10, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 26, 27, 28). Methodological problems, such as in vitro activation of platelets, limited the value of earlier studies. Newly developed analytical tests for molecular markers of the hemostatic system (20) and flow-cytometric techniques for the detection of surface antigens on platelets (25) have enabled more detailed insights into the changes of the hemostatic system during exercise.


Fibrinolytic Activity Fibrinolytic System Heavy Physical Exertion Hemostatic System Fibrin Monomer 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media New York 1996

Authors and Affiliations

  • Martin Möckel
    • 1
  • Natalie-Viviane Ulrich
    • 1
  • Lothar Röcker
    • 2
  • Andreas Ruf
    • 3
  • Frank Klefisch
    • 1
  • Oliver Danne
    • 1
  • Jörn Vollert
    • 1
  • Reinhold Müller
    • 4
  • Thomas Bodemann
    • 5
  • Heinrich Patscheke
    • 3
  • Hermann Eichstädt
    • 6
  • Thomas Störk
    • 7
  • Ulrich Frei
    • 1
  1. 1.Department of Internal MedicineUniversity Hospital Virchow-Klinikum Humboldt UniversityBerlinGermany
  2. 2.Department of PhysiologyFree University BerlinGermany
  3. 3.Institute for Medical LaboratoryDiagnostics Klinikum KarlsruheGermany
  4. 4.Institute for Medical StatisticsFree University BerlinGermany
  5. 5.Rehabilitation Clinic for Cardiovascular Diseases Nikolassee BerlinGermany
  6. 6.Department of Cardiovascular ImagingUniversity Hospital Virchow-Klinikum Humboldt UniversityBerlinGermany
  7. 7.Department of Cardiology/AngiologyKarl Olga HospitalStuttgartGermany

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