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Does Ventilation Ever Limit Human Performance?

  • Craig A. Harms
  • Jerome A. Dempsey
Chapter
  • 179 Downloads

Abstract

Factors which limit human performance have been of interest to both researchers and athletes for many years. While it is well known that human performance is complex and multifaceted, at least in endurance related activities (e.g. running, cycling, etc), success is related to how well an individual is able to introduce, distribute, and utilize oxygen in the body. Maximal oxygen consumption (̇VO2max) is determined by the product of cardiac output and arterio-venous oxygen difference (Fick equation). Specifically, arterial oxygen content is greatly influenced by the effect of pulmonary ventilation and alveolarcapillary diffusion on arterial oxygen pressure (PaO2) and arterial oxygen saturation (SaO2). Therefore, a central question in oxygen transport is whether or not the pulmonary system can serve as a weak link in the oxygen transport chain. Traditionally, oxygen transport is believed to be limited by the heart’s ability to distribute blood and oxygen throughout the body (11). However, in recent years it has been demonstrated that in highly aerobic individuals, the demand of the exercise for O2 transport may exceed the capacity of the respiratory system and therefore lead to impairments in pulmonary gas exchange and consequently lead to exercise induced hypoxemia (EIH). Also, high ventilatory work during intense exercise may contribute to exercise limitation via a high oxygen cost of breathing and therefore “steal” blood flow from limb locomotor muscles. It is the intent of this discussion to focus on some of the possibilities in which the pulmonary system could potentially limit human performance in the young healthy adult.

Keywords

Respiratory Muscle Maximal Exercise Ventilatory Response Endurance Athlete Intense Exercise 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    Aaron, E.A., K.C. Seow, B.D. Johnson, and J.A. Dempsey. Oxygen cost of exercise hyperpnea: implications for performance. J. Appl. Physiol. 72:1818–1825, 1992.PubMedGoogle Scholar
  2. 2.
    Clanton T.L., G.F. Dixon, J. Drake, and J.E. Gadek. Effects of swim training on lung volumes and inspiratory muscle conditioning. J. Appl Physiol. 62:39–46, 1985.Google Scholar
  3. 3.
    Dempsey, J.A., P.G. Hanson, and K.S. Henderson. Exercise-induced arterial hypoxaemia in healthy human subjects at sea level. J. Physiol. 355:161–175, 1984.PubMedGoogle Scholar
  4. 4.
    Harms, C.A., and J.M. Stager. Low chemoresponsiveness and inadequate hyperventilation contribute to exercise-induced hypoxemia. J. Appl Physiol. 79:575–580, 1995.PubMedGoogle Scholar
  5. 5.
    Hopkins, S.R., and D.C. McKenzie. Hypoxic ventilatory response and arterial desaturation during heavy work. J. Appl Physiol. 67:1119–1124, 1989.PubMedGoogle Scholar
  6. 6.
    Johnson, B.D., K.W. Saupe, and J.A. Dempsey. Mechanical constraints on exercise hyperpnea in endurance athletes. J. Appl. Physiol. 73:874–886, 1992.PubMedGoogle Scholar
  7. 7.
    Linstedt, S.L., R.G. Thomas, and D.E. Leith. Does peak inspiratory flow contribute to settingVO2max? Resp. Physiol. 95:109–118, 1994.CrossRefGoogle Scholar
  8. 8.
    Martin, B.J., J.V. Weil, K.E. Sparks, R. McCullough, and R.F. Grover. Exercise ventilation correlates positively with ventilatory chemoresponsiveness. J. Appl. Physiol. 45:557–564, 1978.PubMedGoogle Scholar
  9. 9.
    Powers, S.K., S. Grinton, J. Lawler, D. Criswell, and S. Dodd. High intensity exercise training-induced metabolic alterations in respiratory muscles. Resp. Physiol. 89:169–177, 1992.CrossRefGoogle Scholar
  10. 10.
    Powers, S.K., J. Lawler, J.A. Dempsey, S. Dodd, and G. Landry. Effects of incomplete pulmonary gas exchange oṅVVO2max. J. Appl. Physiol. 66:2491–2495, 1989.PubMedGoogle Scholar
  11. 11.
    Rowell, L. Integration of cardiovascular control systems. In: Handbook of Physiology, edited by L. Rowell New York: Oxford University Press, 1995.Google Scholar
  12. 12.
    Rowell, L.B., and D.S. O’Leary. Reflex control of the circulation during exercise: chemoreflexes and mechanoreflexes. J. Appl. Physiol. 69:407–418, 1990.PubMedGoogle Scholar
  13. 13.
    Secher, N.H., J.P. Clausen, K. Klausen, I. Noer, and J. Trap-Jensen. Central and regional circulatory effects of adding arm exercise to leg exercise. Acta Physiol. Scand. 100:288–297. 1977.PubMedCrossRefGoogle Scholar
  14. 14.
    Wagner, P.D. Influence of mixed venous PO2 on diffusion of O2 across the pulmonary blood:gas barrier. Clin. Physiol. 2:105–115, 1982.PubMedCrossRefGoogle Scholar
  15. 15.
    Weibel, E.R., L.B. Marques, M. Constantinopol, R. Doffey, P. Gehr, and C.R. Taylor. The pulmonary gas exchanger. Resp. Physiol. 69:81–100, 1987.CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 1996

Authors and Affiliations

  • Craig A. Harms
    • 1
  • Jerome A. Dempsey
    • 1
  1. 1.John Rankin Laboratory of Pulmonary Medicine Department of Preventive MedicineUniversity of Wisconsin-MadisonMadisonUSA

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