Determination of the PCO2-Dependent Component of the H+ Concentration in Venous and Arterial Blood Plasma

  • Masaji Mochizuki
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 411)


In normal venous blood plasma, the regression line of [H+] plotted against the PCO2 was linear against the square root of PCO2. Sequential measurements in venous and arterial blood of PCO2 and [H+] showed that the venous-arterial (V-A) difference in [H+] was linearly related to the V-A difference in the square root of PCO2, the regression line having the same slope as that of the venous [H+] plotted against the square root of PCO2. These findings suggested that the venous [H+] on the regression line represents the PCO2dependent component, of [H+], [H+]*. The PCO2-independent component, Δ[H+], can then be given by subtracting [H+]* from the measured [H+]. The Δ[H+] in venous blood agreed well with that in arterial blood with a correlation coefficient of 0.99, supporting the validity of the value of [H+]*.


Regression Line Venous Blood Elderly Group Venous Plasma Interrupted Line 
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Copyright information

© Springer Science+Business Media New York 1997

Authors and Affiliations

  • Masaji Mochizuki
    • 1
  1. 1.Geriatric Respiratory Research CenterNishimaruyama HospitalChuo-KuJapan

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