Skip to main content

Abstract

Whey is a by-product of cheese production, when fat and casein are removed, which is generated at a rate of about 9 kg for every 1 kg of cheese or 6 kg for every 1 kg of cottage cheese (91% of the milk processed). One hundred kilograms of whey are equivalent to the sewage produced by 45 people (Jelen, 1979). At this rate, a medium sized cheese plant discharging 50–150 X 103 kg of whey day-1 constitutes a polluting strength equal to the sewage from 22 500–67 500 people on a daily basis (Modler, 1982). In many countries, including Canada, most of the whey is discarded as waste creating severe pollution problems owing to its biological oxygen demand (BOD) (35 000–40 000 ppm) (Kosikowski, 1976; Scott, 1981). This BOD is due mainly to the lactose which is preent at concentrations of between 4.5% and 5% (Kosikowski, 1976; Garoutte et al., 1983).

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 169.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Aeschlimann, A. and Stockar, U. Von (1989) Biotechnol. Lett., 11, 195.

    Article  CAS  Google Scholar 

  • Aeschlimann, A. and Stockar, U. Von (1990) Appt. Microbiol. Biotechnol., 32, 398.

    Article  CAS  Google Scholar 

  • Aeschlimann, A. and Stockar, U. Von (1991) Enzyme Microbiol. Technol., 13, 811.

    Article  CAS  Google Scholar 

  • Aeschlimann, A., Stasi, L. Di and Stockar, U. Von (1990) Enzyme Microbiol. Technol., 12, 926.

    Article  CAS  Google Scholar 

  • Ahern, W.P., Skogerson, L.E. and Andrist, D.F. (1985) Fermentation of Whey, European patent application, EP 160, 417, November 1985.

    Google Scholar 

  • Amrane, A. and Prigent, Y. (1993) Biotechnol. Lett., 15, 239.

    Article  CAS  Google Scholar 

  • Amrane, A. and Prigent, Y. (1994a) J. Chem. Technol. Biotechnol., 60, 241.

    Article  CAS  Google Scholar 

  • Amrane, A. and Prigent, Y. (1994b) Appt. Microbiol. Biotechnol., 40, 644.

    Article  CAS  Google Scholar 

  • Anderson, T.M. (1982) Mycostatic whey, European patent application, EP 95, 268 (cl. A2 3C21/02), November 1983, US application 379, 841, May 1982.

    Google Scholar 

  • Anderson, T.M., Bodie, E.A., Goodman, N. and Schwartz, (1986) Appt. Environ. Microbiol., 51, 427.

    CAS  Google Scholar 

  • Arasaratnam, V., Senthuran, A. and Balasubramanian, K. (1996) Enzyme Microbiol. Technol., 19, 482.

    Article  CAS  Google Scholar 

  • Arnaud, J.P., Lacroix, C. and Choplin, L. (1992) Biotechnol. Tech., 6, 265.

    Article  CAS  Google Scholar 

  • Audet, P. Pacquin, C. and Lacroix, C. (1988) Appt. Microbiol. Biotechnol., 29, 11.

    Article  CAS  Google Scholar 

  • Audet, P., Lacroix, C. and Paquin, C. (1992) Int. Dairy J., 2, 1.

    Article  CAS  Google Scholar 

  • Bergey’s Manual of Determinative Bacteriology 8th edn, (1974) Williams and Wilkins, Baltimore.

    Google Scholar 

  • Bodie, E.A., Schwartz, R.D. and Anderson (1983) Fermentation of whey for bakery product preservation, European patent application EP141, 642, May 1985, US application 548, 170, November 1983.

    Google Scholar 

  • Bodie, E.A., Anderson, T.M., Goodman, N. and Schwarz, R.D. (1987) Appt. Microbiol. Biotechnol., 25, 434.

    CAS  Google Scholar 

  • Borzani, W. and Baralle, S.B. (1983) Agric. Biol. Technol., 26 (4), 475.

    CAS  Google Scholar 

  • Boyaval, P. and Corre, C. (1987) Biotechnol. Lett., 11, 801.

    Article  Google Scholar 

  • Boyaval, P. and Goulet, J. (1988) Enzyme Microbiol. Technol., 10, 725.

    Article  CAS  Google Scholar 

  • Boyaval, P., Lebrun, A and Goulet, J. (1985) Le Lait, 65, 185.

    Article  CAS  Google Scholar 

  • Boýaval, P., Corre, C. and Terre, S. (1987) Biotechnol. Lett., 9, 207.

    Article  Google Scholar 

  • Boyaval, P., Corre, C. and Terre, S. (1988) Le Lait, 68, 65.

    Article  Google Scholar 

  • Buchta, K. (1983) Lactic acid, in Biotechnology (ed. H.J. Rehm and G. Reed), Biomass, Microorganisms, Energy from Renewable Resources, Vol. 3, Verlag Chemie, Weinheim, p. 409.

    Google Scholar 

  • Campbell, L.A. (1953) Can. Dairy Ice Cream J., 32, 29, 77.

    Google Scholar 

  • Campbell, M.E. and Glenn, W.M. (1982) Profit from Pollution Prevention - A Guide to Industrial Waste Reduction of Recycling. Pollution Probe Foundation Report, Toronto, Ontario.

    Google Scholar 

  • Carronodo, M.J.T., Crespo. J.P.S.G. and Moura, M.J. (1988) Appt. Biotechnol., 17, 295.

    Article  Google Scholar 

  • Cavin, J.F., Saint, C. and Divies, C. (1985) Biotechnol. Lett., 7, 821.

    Article  CAS  Google Scholar 

  • Champagne, C.P. and Boyaval, P. (1986) Techn. Lait Marketing, 1015, 26.

    Google Scholar 

  • Champagne, C.P., Baillargeon-Cote, C. and Goulet, J. (1989) J. Appt. Bacteriol., 66, 175.

    Article  CAS  Google Scholar 

  • Cheng, P., Muller, S., Bajpai, R. and Lannotti, E.J. (1991) J. Ind. Microbiol., 7, 27.

    Article  CAS  Google Scholar 

  • Chiarini, L., Mara, L. and Tabacchioni, S. (1992) Appt. Microbiol. Biotechnol., 36, 461.

    CAS  Google Scholar 

  • Clausen, E.C. and Gaddy, J.L. (1984) Chem. Eng. Progress, 80, 59.

    CAS  Google Scholar 

  • Clausen, E.C., Shah, R.B., Najafpour, G. and Gaddy, J.L. (1982) Biotechnology and Bioengineering Symposium Series, no. 12 (ed. C.D. Scott), Wiley, New York, pp. 67–72.

    Google Scholar 

  • Colomban, A., Roger, L. and Boyaval, P. (1993) Biotechnol. Bioeng., 42, 1091.

    Article  CAS  Google Scholar 

  • Compere, A.L. and Griffith, W.L. (1975) Dev. Ind. Microbiol., 17, 247.

    Google Scholar 

  • Cox, G.C. and MacBean, R.D. (1977) Aust. J. Dairy Technol., 32, 19.

    CAS  Google Scholar 

  • Coulman, R.A., Stieber, R.W. and Gerhardt, P. (1977) Appt. Env. Microbiol., 34, 725.

    CAS  Google Scholar 

  • Dairy Market Review (1982) Marketing and Economics Branch, Agriculture Canada, Ottawa, August.

    Google Scholar 

  • Denirci, A., Pometto, A.L., III and Johnson, K.E. (1993) Appt. Environ. Microbiol., 59, 203.

    Google Scholar 

  • Divies, C. and Siess, M.H. (1976) Ann. Microbiol., Inst. Pasteur, 127B, 525.

    Google Scholar 

  • Emde, R. and Schink, B. (1990) Appt. Eпv. Microbiol., 56, 2771.

    CAS  Google Scholar 

  • Friedman, M.R. and Gaden, E.L., Jr (1970) Biotechnol. Bioeng., 12, 961.

    Article  CAS  Google Scholar 

  • Galpin, D.B. (1981) N. Zeal. J. Dairy Sci. Technol., 16, 289.

    Google Scholar 

  • Garoutte, C., Lim, J., Amundson, C.H. and Breslau, B. (1983) Process Biochem., 18, 2.

    Google Scholar 

  • Gatje, W. and Gottschalk, G. (1991) Appi. Microbiol. Biotechnol., 34, 446.

    Google Scholar 

  • Gerhardt, P. and Reddy, C.A. (1978) Dev. Ind. Microbiol., 19, 71.

    Google Scholar 

  • Gonsalves, L.M.D., Xavier, A.M.R.B., Almeida, J.S. and Corrondo, M.J.T. (1991) Enzyme Microbiol. Technol., 13, 314.

    Article  Google Scholar 

  • Goursaud, J. (1986) Ind. Aliment. Agric., 103, 349.

    CAS  Google Scholar 

  • Groves, F. (1972) Proceedings of the Whey Products Conference, Agriculture Research Service, US Department of Agriculture, ERRL publication no. 3779, p. 5.

    Google Scholar 

  • Haddadin, M.D., Al Muhirat, S.R., Batayneh, N. and Robinson, R.K. (1996) J. Soc. Dairy Technol., 49, 79.

    Article  CAS  Google Scholar 

  • Hamilton, K.M. and Howell, J.A. (1983) Advances in Fermentation 83, Proceedings of a Conference on Wheatland, Rickmansworth, Chelsea College, University of London, September, p. 171.

    Google Scholar 

  • Hanson, T.P. and Tsao, G.T. (1972) Biotechnol. Bioeng., 14, 233.

    Article  CAS  Google Scholar 

  • Hongo, M., Nomura, Y. and Iwahara, M. (1986) Appl. Environ. Microbiol., 52, 314.

    CAS  Google Scholar 

  • Hsu, S.T. and Yang, S.T. (1991) Biotechnol. Bioeng., 38, 571.

    Article  CAS  Google Scholar 

  • Ioтdan, E.P., Ikonnikov, N.P., Kovrizhnykh, V.A. and Vorob’eva, L.I. (1980) Appl. Biochem. Microbiol., 40, 465.

    Google Scholar 

  • Jain, D.K., Tyagi, R.D., Kluepfel, D. and Agbebavi, J.T. (1991) Process Biochem., 26, 217.

    Article  CAS  Google Scholar 

  • Jelen, P. (1979) J. Agric. Food Chem., 27, 658.

    Article  CAS  Google Scholar 

  • Kandler, O. (1982) Forum Microbiol., 5, 16.

    CAS  Google Scholar 

  • Keller, A.K. and Gerhardt, P. (1975) Biotechnol. Bioeng., 17, 997.

    Article  CAS  Google Scholar 

  • Kennedy, P.K. (1985) Cult. Dairy Prod. J., 20, 13.

    CAS  Google Scholar 

  • Kosaric, N. and Asher, Y.J. (1985) Adv. Biochem. Eng. Biotechnol., 32, 25.

    CAS  Google Scholar 

  • Kosaric, N. and Wieczorek, A. (1984) Dev. Food Sci., 9, 229.

    CAS  Google Scholar 

  • Kosikowski, F.V. (1976) Cheese and Fermented Milk Foods, Edward Brothers, Ann Arbor, MI.

    Google Scholar 

  • Kovach, M.P. and Meyerhoff, M.E. (1982) Anal. Chem., 54, 217.

    Article  CAS  Google Scholar 

  • Krischke, W., Schroder, M. and Trosch, W. (1991) Appt. Microbiol. Biotechnol., 34, 573.

    Article  CAS  Google Scholar 

  • Lacroix, C., Paquin, C. and Arnaud, J.P. (1990) Appt. Microbiol. Biotechnol., 32, 403.

    Article  CAS  Google Scholar 

  • Lee, K.H. (1981) Hanguk Nonghwa Hakhoe Chi (Korean), 24, 149.

    CAS  Google Scholar 

  • Lee, I.H., Fredrickson, A.G. and Tsuchiya, M.H. (1974) Appt. Microbiol., 28, 831.

    CAS  Google Scholar 

  • Leudeking, R. and Piret, E.L. (1956) J. Biochem. Microbiol. Technol. Eng., 1, 513.

    Google Scholar 

  • Levenspiel, O. (1962) Chemical Reaction Engineering, Wiley, New York.

    Google Scholar 

  • Lewis, V.P. and Yang, S.T. (1992a) Biotechnol. Progress, 8, 104.

    Article  CAS  Google Scholar 

  • Lewis, V.P. and Yang, S.T. (1992b) Biotechnol. Bioeng., 40, 465.

    Article  CAS  Google Scholar 

  • Lund, B., Norddahl, B. and Ahring, B. (1992) Biotechnol. Lett., 14, 851.

    Article  CAS  Google Scholar 

  • Major, N.C. and Bull, A.T. (1985) Biotechnol. Lett., 7, 401.

    Article  CAS  Google Scholar 

  • Major, N.C. and Bull, A.T. (1989) Biotechnol. Bioeng., 34, 592.

    Article  CAS  Google Scholar 

  • Marri;ott, T.A. (1985) J. Soc. Dairy Technol., 38, 109.

    Article  Google Scholar 

  • Marshall, K.R. and Earle, R.L. (1975) N. Zeal. J. Dairy Sci. Technol., 10, 123.

    CAS  Google Scholar 

  • Matsunaga, T., Karube, I. and Suzuki, S. (1978) Anal. Chem. Acta, 98, 25.

    Article  CAS  Google Scholar 

  • Mehaia, M.A. and Cheryan, M. (1986) Enzyme Microbiol. Technol., 8, 289.

    Article  CAS  Google Scholar 

  • Mehaia, M.A. and Cheryan, M. (1987) Appl. Biochem. Biotechnol., 14, 21.

    Article  CAS  Google Scholar 

  • Mistry, V.V., Kosikowski, F.V. and Bellamy, W.D. (1987) J. Dairy Sci., 70, 2220.

    Article  CAS  Google Scholar 

  • Modler, H.W. (1982) Cult. Dairy Prod. J., 17, 11.

    Google Scholar 

  • Moebus, O. and Teuber, M. (1986) Kiel. Milchwirtsch. Forschungsber., 38, 119.

    CAS  Google Scholar 

  • Morimura, S., Kishimoto, M. and Kida, K. (1986) Organic acid production by immobilized microbe. Japanese patent 61 56, 087, March 1986.

    Google Scholar 

  • Muller, P.G. (1979) Economic Evaluation of Feeding Liquid Whey to Livestock, Technical report, Food Research Institute, Research Branch, Agriculture Canada, Ottawa.

    Google Scholar 

  • Mulligan, C.N., Safi, B.F. and Groleau, D. (1991) Biotechnol. Bioeng., 38, 1173.

    Article  CAS  Google Scholar 

  • Mzali, J. (1992) M.Sc. thesis. I. N.R.S.-Eau, University of Quebec.

    Google Scholar 

  • Nagai, S., Ozaki, M., Fukunishi, K. and Yamazaki, K. (1986) Immobilized microorganisms for production of lactic acid and other substances, Japanese patent no. 61 58, 588, March 1986.

    Google Scholar 

  • Nanba, A., Nukada, R. and Nagai, S. (1983) J. Ferment. Technol., 61, 551.

    CAS  Google Scholar 

  • Nickerson, T.K. (1974) In Fundamentals of Dairy Chemistry, 2nd edn (ed. B.H. Webb, A.M. Johnson and J.A. Alford), AVI, Westport, CT, p. 273.

    Google Scholar 

  • Nicolas, C.M. and Bull, A.N. (1985) Biotechnol. Lett., 7, 401.

    Article  Google Scholar 

  • Nielson, J., Nikolajsen, K. and Villadsen, J. (1991) Biotechnol. Bioeng., 38, 1.

    Article  Google Scholar 

  • Norton, S., Lacroix, C. and Vuillemard, J.C. (1994a) J. Dairy Sci., 77, 2949.

    Article  Google Scholar 

  • Norton, S., Lacroix, C. and Vuillemard, J.C. (1994b) Food Biotechnol., 7, 235.

    Article  Google Scholar 

  • Norton, S., Lacroix, C. and Vuillemard, J.C. (1994c) Enzyme Microbiol. Technol., 16, 457.

    Article  CAS  Google Scholar 

  • Ohleyer, E., Blanch, H.W. and Wilke, C.R. (1985) Appt. Biochem. Biotechnol., 11, 457.

    Article  CAS  Google Scholar 

  • Ohmiya, K., Ohashi, H., Kobayashi, T. and Shimizu, S. (1977) Appt. Environ. Microbiol., 33, 137.

    CAS  Google Scholar 

  • Prescott, S.C. and Dunn, C.G. (1949) Industrial Microbiology, 2nd edn, McGraw-Hi11, New York, chapter 21.

    Google Scholar 

  • Prigent, Y. (1983) Method and apparatus for the continuous preparation of lactic acid by fermentation of whey, French patent demande Fr 2, 555, 200, May 1985, application 83 /18, 631, November 1983.

    Google Scholar 

  • Raucourt, A. De, Girars, D., Prigent, Y. and Boyaval, P. (1989a) Appt. Microbiol. Biotechnol., 30, 521.

    Google Scholar 

  • Raucourt, A. De, Girars, D., Prigent, Y. and Boyaval, P. (1989b) Appt. Microbiol. Biotechnol., 30, 528.

    Google Scholar 

  • Reddy, C.A., Henderson, H.E. and Erdman, M.D. (1976) Appt. Environ. Microbiol., 32, 776.

    Google Scholar 

  • Rehberger, T.J. and Glatz, B.A. (1990) Appt. Env. Microbiol., 56, 864.

    CAS  Google Scholar 

  • Riddle, M.J. and Chandler, W.D. (1974) Proceedings of the Whey Utilization Symposium, June, Ottawa, Ontario.

    Google Scholar 

  • Ripley, P. (1979) Process Biochem., 14–18.

    Google Scholar 

  • Roy, D., Goulet, J. and LeDuy, A. (1986) Appt. Microbiol. Biotechnol., 24, 206.

    CAS  Google Scholar 

  • Roy, D., Goulet, J. and Leduy, A. (1987) J. Dairy Sci., 70, 506.

    Article  CAS  Google Scholar 

  • Schuppert, B., Schink, B. and Trosch, W. (1992) Appt. Microbiol. Biotechnol., 37, 549.

    CAS  Google Scholar 

  • Scott, R. (1981) Cheesemaking Practice, Applied Science Publishers, London.

    Google Scholar 

  • Silva, E. and Yang. S.T. (1995) J. Biotechnol., 41, 59.

    Article  CAS  Google Scholar 

  • Singh, R.K. and Ghaly, А.Е. (1984) Agricultural Waste Utilization and Management, Proceedings of the 5th International Symposium on Agricultural Wastes, Chicago, IL, ASAE Publication 13–85, p. 546.

    Google Scholar 

  • Somkuti, G.A. and Steinberg, D.H. (1979) J. Food Protection, 42, 885.

    CAS  Google Scholar 

  • Steffen, C., Nick, B. and Blanch, B.H. (1973) Schweiz. Milchw. Forsch., 2, 37.

    Google Scholar 

  • Stenroos, S.L., Lindo, Y.Y. and Lenko, P. (1982) Biotechnol. Lett., 4, 159.

    Article  CAS  Google Scholar 

  • Stieber, R.W. and Gerhardt, P. (1979a) Appt. Environ. Microbiol., 37, 487.

    CAS  Google Scholar 

  • Stieber, R.W. and Gerhardt, P. (1979b) J. Dairy Sci., 62, 1558.

    Article  CAS  Google Scholar 

  • Stieber, R.W. and Gerhardt, P. (1981a) Biotechnol. Bioeng., 23, 535.

    Article  CAS  Google Scholar 

  • Stieber, R.W. and Gerhardt, P. (1981b) Biotechnol. Bioeng., 23, 535.

    Article  CAS  Google Scholar 

  • Stieber, R.W., Coulman, G.А. and Gerhardt, P. (1977) Appt. Env. Microbiol., 34, 733.

    CAS  Google Scholar 

  • Tewari, H.K., Seth, R.P., Sood, A. and Singh, L. (1985) J. Res. Punjab Agricul. Univ., 22, 89.

    Google Scholar 

  • Tsao, G.T. and Hanson, T.P. (1975) Biotechnol. Bioeng., 17, 1591.

    Article  Google Scholar 

  • Tuli, A., Sethi, R.P., Khanna, P.K., Marwaha, S.S. and Kennedy, J.F. (1985) Enzyme Microbiol. Technol., 7, 164.

    Article  CAS  Google Scholar 

  • Tyagi, R.D. (1986) Evaluation of Dairy Industry Waste (Cheese Whey) as Substrate for Bioconversion, Scientific Report, I. N.R.S.-Eau, University of Québec.

    Google Scholar 

  • Vahvaselka, M.I. and Linko, P. (1987) Proceedings of the 4th European Congress on Biotechnology, Vol. 3 (eds O.M. Neyssel, R.R. Van der Meer and K.C.A.M. Huyben), Elsevier, Amsterdam, p. 317.

    Google Scholar 

  • Vick Roy, T.B., Blanch, H.V. and Wilke, C.R. (1982) Biotechnol. Lett., 4, 483.

    Article  Google Scholar 

  • Vick Roy, T.B., Mandat, D.K., Dea, D.K., Blanch and Wilke, C.R. (1983) Biotechnol. Lett., 5, 665.

    Article  Google Scholar 

  • Vinegra-Gonzaliz, G. and Gomez, J. (1983) In Bioconversion Systems (ed. D. Wise), CRC Press, Boca Raton, FL, p. 17.

    Google Scholar 

  • Woksow, S.A. and Glatz, B.A. (1991) Appt. Env. Microbiol., 57, 2821.

    Google Scholar 

  • Yabamavar, V.M. and Wang, D.I.C. (1991) Biotechnol. Bioeng., 37, 544.

    Article  Google Scholar 

  • Yang, S.T., Zhu, H., Li, Y. and Hong, G. (1994) Biotechnol. Bioeng., 43, 1124.

    Article  CAS  Google Scholar 

Download references

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1998 Springer Science+Business Media New York

About this chapter

Cite this chapter

Tyagi, R.D., Kluepfel, D. (1998). Bioconversion of cheese whey to organic acids. In: Martin, A.M. (eds) Bioconversion of Waste Materials to Industrial Products. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-5821-7_9

Download citation

  • DOI: https://doi.org/10.1007/978-1-4615-5821-7_9

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-7668-2

  • Online ISBN: 978-1-4615-5821-7

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics