Abstract
The contribution of reperfusion to ischemia induced brain damage is considered to be a serious phenomenon seen after global and/or regional ischemic insult and accompanied by multiple biochemical and electrophysiological changes during the recovery phase. The application of graded postischemic reoxygenation in various ischemic models may significantly improve the functional recovery, neuropathological outcome (1,2,3), blood-brain-barier permeability (4), and protein synthesis inhibition (5). Therefore, the response of four inner membrane phospholipids, i.e., phosphatidylserine (SP), ethanolamine plas-malogens (Epls), phosphatidylinositol (IP), and phosphatidic acid (PA) was studied after normoxic (NR) versus graded postischemic reoxygenation (GPIR) in a reliable ischemic model of a rabbit’s spinal cord (6) and compared with the neuropathological outcome made at light (LM) and electronmicroscopic (EM) levels.
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Lukáçová, N., Marsala, M., Marsala, J. (1997). Graded Postischemic Reoxygenation, Phospholipids and Neuronal Damage in Rabbits after Ischemia. In: Teelken, A., Korf, J. (eds) Neurochemistry. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-5405-9_77
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DOI: https://doi.org/10.1007/978-1-4615-5405-9_77
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