Skip to main content

The Effect of Contact Lenses on the Conjunctiva

  • Chapter
Advances in Corneal Research
  • 185 Accesses

Abstract

The purpose of this paper is to review the effects contact lenses have on the conjunctiva. A review of the literature of the effects of contact lenses on conjunctival sensitivity, epithelial cells, bacterial flora, and inflammation reveals that contact lenses have no effect on bulbar conjunctival sensitivity, but appear to cause a decrease in the sensitivity of the tarsal conjunctiva and the lower lid margin. However, contact lens wear does cause an increase in mucous production and an increase in mucous-containing vesicles in the epithelial cells, as well as an increase in goblet cells. They may also cause squamous metaplasia with enlarged flattened epithelial cells, without evidence of keratinization, as well as snake-like changes in the conjunctival epithelium. Contact lenses do not have a significant effect on the conjunctival flora, but may affect the eye’s ability to eliminate microorganisms that are introduced. In addition, contact lens care solutions can cause a toxic or allergic reaction causing conjunctival erythema and chemosis with involvement of the cornea. Chlorhexidine and thimerosal appear to be two solutions with the highest incidence of allergic response. Also, either a poor contact lens fit or the use of thimerosal cancause a syndrome that mimics superior bulbar conjunctivitis of Theodore. The contact lens, especially when coated, can cause giant papillary conjunctivitis. Results of this review indicate that in the majority of patients, contact lens wear has little effect on the conjunctiva. However, a contact lens is a foreign body and can cause changes that can affect the conjunctiva

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. L.G. Lawrenson, and Ruskell, C.L., Investigation of limbal touch sensitivity using a Cochet-Bonnet aesthesiometer. Br. J. Ophthalmol. 77:339 (1993).

    Article  PubMed  CAS  Google Scholar 

  2. D.P. McGowan, Lawrenson, J.G., and Ruskell, G.L., Touch sensitivity of the eyelid margin and palpebrai conjunctiva. Acta Ophthalmology 72:57 (1994).

    Article  CAS  Google Scholar 

  3. J.M. Dickson, Ocular changes due to contact lenses. Am. J. Ophthalmol. 58:424 (1964).

    Google Scholar 

  4. G.E. Lowther, and Hilt, R.M., Sensitivity threshold of the lower lid margin in the course of adaptation to contact lenses. Am. J. Ophthalmol. 45:587 (1968).

    CAS  Google Scholar 

  5. J.V. Greiner, and Allansmith, M.R., Effect of contact lens wear on the conjunctival mucous system. Ophthalmol. 88:821 (1981).

    CAS  Google Scholar 

  6. C.G. Connor, Campbell, J.B., Steel, C.A., and Burke, J.H., The effect of daily wear contact lenses on goblet cell density. J. Am. Optometric. Assoc. 65:792 (1994).

    CAS  Google Scholar 

  7. P.E. Knop, and Brewitt, H., Conjunctival cytology in asymptomatic wearers of soft contact lenses. Graefes Arch. Clin. Exper. Ophthalmol. 230:340 (1992)

    Article  CAS  Google Scholar 

  8. O.H. Winkler, and Dixon, J.M., Bacteria of the eye. Arch. Ophthalmol. 72:817 (1964).

    Article  PubMed  Google Scholar 

  9. F.M. Kepetansky, Suie, T., Gracy, A.D., and Bitonte, J.L., Bacteriologic studies of patients who wear contact lenses. Am. J. Ophthalmol. 57:255 (1964).

    Google Scholar 

  10. P.S. Binder, and Worthen, D.M., A continuous wear hydrophilic lens. Prophylactic topical antibiotics. Arch. Ophthalmol. 94:2109 (1976).

    Article  PubMed  CAS  Google Scholar 

  11. G. Hovding, Conjunctival and contact lens bacterial flora during continuous “bandage lens” wear. Acta Ophthalmol. 60:439 (1982).

    CAS  Google Scholar 

  12. M. Rydberg, Bacteriology in continuous wear of soft contact lenses. Contact Intraocul Lens Med. J. 1:150 (1975).

    Google Scholar 

  13. S.M.J. Fleiszig, and Efron, N., Microbial flora in eyes of current and former contact lens wearers. J. Clin. Microbiol. 30:1156 (1992)

    PubMed  CAS  Google Scholar 

  14. D.F. Larkin, and Leeming, J.P., Quantitative alterations of the commensal eye bacteria in contact lens wear. Eye 5:70 (1991).

    Article  PubMed  Google Scholar 

  15. S.M.J. Fleiszig, and Efron, N., Conjunctival flora in extended wear of rigid gas permeable contact lenses. Optometry Vis. Sci. 69:354 (1992).

    Article  CAS  Google Scholar 

  16. G. Smolin, Okumoto, M., and Nozik, R.A., Microbial flora in extended wear soft contact lens wearers. Am. J. Ophthalmol. 88:543 (1979).

    PubMed  CAS  Google Scholar 

  17. B.D. Coward, Neumann, R., and Callender M: Solutions intolerance among users of four chemical soft tens care regimens. Am. J. Optom. Physiol. Opt. 61:523–527 (1984).

    Article  PubMed  CAS  Google Scholar 

  18. F.H. Theodore, Superior limbic keratoconjunctivitis. Eye, Ear, Nose and Throat Month 42:25 (1964).

    Google Scholar 

  19. F.H. Theodore, and Ferry, A.P., Superior limbic keratoconjunctivitis — Clinical and pathological correlations. Arch. Ophthalmol. 84:481 (1970).

    Article  PubMed  CAS  Google Scholar 

  20. S. Stenson, Superior limbic keratoconjunctivitis associated with soft contact lens wear. Arch. Ophthalmol. 101:402 (1983).

    Article  PubMed  CAS  Google Scholar 

  21. D.D. Sendele, Kenyon, K.R., and Mobilia, E.R., Superior limbic keratoconjunctivitis in contact lens wearers. Ophthalmology 90:616 (1983).

    PubMed  CAS  Google Scholar 

  22. T.F. Spring, Reaction to hydrophilic lenses. Med. J. Aust. 1:499 (1974).

    Google Scholar 

  23. P.C. Palmisano, Ehlers, W.H., and Donshik, P.C., Causative factors in unilateral giant papillary conjunctivitis. CLAO J. 19:103 (1993).

    PubMed  CAS  Google Scholar 

  24. D.R. Korb, Allansmith, M.R., Greiner, J.V., et at., The prevalence of conjunctival changes in wearers of hard contact lenses. Am. J. Ophthalmol. 90:336 (1980).

    PubMed  CAS  Google Scholar 

  25. M.R. Allansmith, Korb, D.R, and Greiner, J.V., Giant papillary conjunctivitis induced by hard or soft contact lens wear: quantitative histology. Ophthalmology 85:766 (1978).

    PubMed  CAS  Google Scholar 

  26. P.C. Donshik, and Ballow, M., Tear immunoglobulins in giant papillary conjunctivitis induced by contact lenses. Am. J. Ophthalmol. 96:460 (1983).

    PubMed  CAS  Google Scholar 

  27. M. Ballow, Donshik, P.C., and Mendelson, L., Complement proteins in C3 anaphylatoxin in the tears of patients with conjunctivitis. J. Allergy Clin. Immunol. 76:473 (1985).

    Article  PubMed  CAS  Google Scholar 

  28. P. Rapacz, Tedesco, J., Donshik, P.C., et al, Tear lysozyme and lactoferrin levels in giant papillary conjunctivitis and vernal conjunctivitis. CLAD J. 14:207 (1988).

    CAS  Google Scholar 

  29. S.A. Elgebaly, Donshik, P.C., Rahhal, F., et al., Neutrophilic chemotactic factors in the tears of giant papillary conjunctivitis patients. Invest. Ophthalmol. Vis. Sci. 32:208 (1991).

    PubMed  CAS  Google Scholar 

  30. W.H. Ehlers, Donshik, P.C., Gillies, C., et al, The induction of an inflammatory reaction by chemotactic factors derived from conjunctival cells. Invest. Ophthalmol. Vis. Sci. 31:241 (1990).

    Google Scholar 

  31. P. J. Caroline, Robbin, J.B., Greiner, J.V., et al, Microscopic and elemental analysis of deposits on extended wear soft contact lenses. CLAO J. 11:311–316 (1985).

    PubMed  CAS  Google Scholar 

  32. O.G. Gudmundsson, Woodward, D.F., Fowler, S.A., et al., Identification of proteins in contact lens surface deposits by immunofluorescence microscopy. Arch. Ophthalmol. 103:196 (1985).

    Article  PubMed  CAS  Google Scholar 

  33. J.T. Barre, Dugan, P.R., Reindeer, W., et al., Protein and element analysis of contact lenses of patients with superior limbic keratoconjunctivitis and GPC. Optom. Vis. Sci. 66:133 (1989).

    Article  Google Scholar 

  34. S.A. Fowler, Greiner, J.V., and Allansmith, M.R., Soft contact lenses from patients with giant papillary conjunctivitis. Am. J. Ophthalmol. 88:1056 (1979).

    PubMed  CAS  Google Scholar 

  35. M. Bellow, Donshik, P.C., Rapacz, P., et al., Immunological response in Cynomolgus monkeys to lenses from patients with contact lens-induced giant papillary conjunctivitis. CLAO J. 15:64 (1989).

    Google Scholar 

  36. P.C. Donshik, Giant papillary conjunctivitis. Trans. Am. Ophthalmol. Soc. XclI (1994).

    Google Scholar 

  37. D.M. Meisler, Berzins, U.J., Krachmer, J.H., et al., The treatment of giant papillary conjunctivitis. Arch. Ophthalmol. 100:1609 (1982).

    Article  Google Scholar 

  38. C.J. Kruger, Ehlers, W.H., Luistro, A.F., et al, The treatment of giant papillary conjunctivitis with Cromolyn sodium. CLAO J. 1 8:46 (1992).

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1997 Springer Science+Business Media New York

About this chapter

Cite this chapter

Donshik, P.C. (1997). The Effect of Contact Lenses on the Conjunctiva. In: Lass, J.H. (eds) Advances in Corneal Research. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-5389-2_38

Download citation

  • DOI: https://doi.org/10.1007/978-1-4615-5389-2_38

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-7460-2

  • Online ISBN: 978-1-4615-5389-2

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics