Skip to main content

Penetrating Keratoplasty for Pseudophakic Bullous Keratopathy

An Indian Experience

  • Chapter
Advances in Corneal Research

Abstract

A retrospective analysis of 198 eyes with pseudophakic bullous keratopathy undergoing penetrating keratoplasty with or without intraocular (IOL) exchange was performed over an 11-year period. The 198 eyes evaluated consisted of 86 anterior chamber (AC), 27 iris fixated (IF), and 85 posterior chamber (PC) lenses. Patients were followed up for an average of 3.2 ± 1.3 years. The mean intervals between initial cataract surgery and penetrating keratoplasty were 38 ± 4, 44 ± 3, and 3 ± 1.2 months with AC, IF and PC lenses, respectively. Pre-existing endothelial changes in fellow eyes were present in 56% of cases. Anterior vitrectomy was performed in 93% of AC, 54% of IF, and 35% of PC lenses. More than half of the PC lenses (58.8%) were retained as opposed to 1.7% of AC lenses and 0% of IF lenses. Maximum grafts remained clear with posterior chamber implants (83%) at the time of mean follow up. Visual acuity of 6/18 or more was achieved in 15% of eyes with AC, 17% with IF, and 45% PC with implants respectively. The most common cause of graft failure was raised intraocular pressure with all types of pseudo- phakos. The leading causes of non-improvement of vision in the presence of clear graft were cystoid macular edema (40%) and glaucomatous optic atrophy (37.1%).

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. R.E. Smith, McDonald, H.R., Nesburn, A.B., and Minckler, D.S., P.K., Changing indications 1947 to 1978. Arch. Ophthalmol. 98:1226 (1980).

    Article  PubMed  CAS  Google Scholar 

  2. J.B. Robin, Gindi, J.J., Koh, K., et al., An update of the indications for keratoplasty 1979 through 1983 Arch. Ophthalmol 104(1):87 (1986

    Article  PubMed  CAS  Google Scholar 

  3. D.M. Taylor, Atlas, B.F., Romanchuk, K.G., and Stern, A.L., Pseudophakic bullous keratopathy. Ophthalmology 90(1): 19 (1983).

    PubMed  CAS  Google Scholar 

  4. P. Haaman, Jensen, O.M., and Schmidt, P., Changing indications of penetrating keratoplasty. Acta Ophthalmol. 72(4):443 (1994).

    Google Scholar 

  5. F.W. Price, Whitson, W.E., Collins, K.S., and Marks, R.G., Five year corneal graft survival. A large, single-center patient cohort. Arch. Ophthalmol. 111(6):799 (1993).

    Article  PubMed  Google Scholar 

  6. R.F. Meyer, and Sugar, A., P.K. in pseudophakic bullous keratopathy 90:677 (1980).

    CAS  Google Scholar 

  7. K.H. Charlton, Binder, P.S., and Perl T., Visual prognosis in pseudophakic corneal transplants. Ophthalmic Surg. 12(6):411 (1981).

    PubMed  CAS  Google Scholar 

  8. J.J. Arentsen, and Laibson, P.R., Surgical management of pseudophakic corneal edema: complications and visual results following penetrating keratoplasty. Ophthalmic Surg. 13(5):371 (1982).

    PubMed  CAS  Google Scholar 

  9. W.R. Fagadau, Maumenee, A.E., Stark, W.J., and Datiles, M., Posterior chamber intraocular lenses at the Wilmer Institute: a comparative analysis of complications and visual results. Br. J. Ophthalmol. 68(1): 13 (1984).

    Article  PubMed  CAS  Google Scholar 

  10. E.J. Cohen, Brady, S.E., Leavitt, K.L., et al., Pseudophakic bullous keratopathy. Am. J. Ophthalmol. 106:264 (1988).

    Article  PubMed  CAS  Google Scholar 

  11. G.N. Rao, Aquavella, J.V., Goldberg S.H., and Berk, S.L., Pseudophakic bullous keratopathy. Relationship to pre-operative endothelial status. Ophthalmology 91(10):1135 (1984).

    PubMed  CAS  Google Scholar 

  12. S.B. Koenig, and Schultz, R.O., Penetrating keratoplasty for pseudophakic bullous keratopathy after extra-capsular cataract extraction. Am. J. Ophthalmol 105:348 (1988).

    Article  PubMed  CAS  Google Scholar 

  13. M. Lugo, Cohen, E.J., Eagle, R.C., et al., The incidence of preoperative endothelial dystrophy in pseudophakic bullous keratopathy. Ophthalmic Surg. 19:16 (1988).

    PubMed  CAS  Google Scholar 

  14. S.R. Waltman, Penetrating keratoplasty for pseudophakic bullous keratopathy. Visual results. Arch. Ophthalmol. 99(3):415 (1981).

    Article  PubMed  CAS  Google Scholar 

  15. M. Busin, Arffa, R.C., McDonald B., and Kaufman, H.E., Intraocular lens removal during penetrating keratoplasty for pseudophakic bullous keratopathy. Ophthalmology 94:505 (1987).

    PubMed  CAS  Google Scholar 

  16. P.W. Smith, Wong, S.K., Stark, W.J., et al., Complications of semiflexible, closed loop anterior chamber intraocular lenses. Arch. Ophthalmol. 105:52 (1987).

    Article  PubMed  CAS  Google Scholar 

  17. G.O. Waring, Stulting, R.D., and Street, D., Penetrating keratoplasty for pseudophakic corneal edema with exchange of intraocular lenses. Arch. Ophthalmol. 105:58 (1987).

    Article  PubMed  Google Scholar 

  18. D.J. Apple, and Olson, R.J., Closed loop anterior chamber lenses. Arch. Ophthalmol. 105:19 (1987).

    Article  Google Scholar 

  19. A.M. Kozarsky, Stopak, S., Waring, G.O., et al., Results of penetrating keratoplasty for pseudophakic corneal oedema with retention of intraocular lens. Ophthalmology 91(10):1141 (1984).

    PubMed  CAS  Google Scholar 

  20. M.S. Insler, Craig, J., Helm, B.S., and Kaufman, B.E., Visual results after keratoplasty in patients with P/C IOL. Am. J. Ophthalmol. 106:72 (1988).

    Article  PubMed  CAS  Google Scholar 

  21. G.O. Waring, Welch, S.N., Cavanagh, H.D., and Wilson, L.A., Results of penetrating keratoplasty in 123 eyes with pseudophakic or aphakic corneal edema. Ophthalmology 90(1):25 (1983).

    PubMed  Google Scholar 

  22. S.G. Kramer, Cystoid macular edema after aphakic penetrating keratoplasty. Ophthalmology 88(8):782 (1981).

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1997 Springer Science+Business Media New York

About this chapter

Cite this chapter

Panda, A., Sharma, N., Angra, S.K. (1997). Penetrating Keratoplasty for Pseudophakic Bullous Keratopathy. In: Lass, J.H. (eds) Advances in Corneal Research. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-5389-2_19

Download citation

  • DOI: https://doi.org/10.1007/978-1-4615-5389-2_19

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-7460-2

  • Online ISBN: 978-1-4615-5389-2

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics