Hypertensive Heart Disease, Ventricular Dysrhythmias, and Sudden Death

  • Franz H. Messerli
  • Leszek Michalewicz
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 432)


Left ventricular hypertrophy (LVH) has been identified as one of the strongest pressure-independent risk factors for sudden death, acute myocardial infarction, congestive heart failure and other cardiovascular morbidity and mortality. [1,2,3] These findings clearly abolish the concept of LVH being a benign adaptive process serving to compensate for the increased hemodynamic burden. Fig. 1. Based on these epidemiologic observations, a patophysiologic or electrophysiologic chain of evidence linking hypertension, LVH, and sudden death has been put forward. Although it is unclear whether a reduction in LVH confers benefit over and above the benefit of lowering blood pressure alone, the effects various antihypertensive agents have on LVH come under scrutiny.


Left Ventricular Hypertrophy Ventricular Arrhythmia Sudden Cardiac Death Left Ventricular Mass Hypertensive Heart Disease 
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Copyright information

© Springer Science+Business Media New York 1997

Authors and Affiliations

  • Franz H. Messerli
    • 1
  • Leszek Michalewicz
    • 1
  1. 1.Department of Internal Medicine Section on Hypertensive DiseasesOchsner Clinic and Alton Ochsner Medical FoundationNew OrleansUSA

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