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Left Ventricular Hypertrophy and Sympathetic Activity

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Book cover Hypertension and the Heart

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 432))

Abstract

Pressure and/or volume overload has been regarded in the past as the leading mechanism through which an increase in blood pressure may trigger the development of left ventricular hypertrophy1. However, studies performed in recent years both in experimental animals and in man have suggested that not only mechanical but also sympathetic, genetic and hormonal factors (e.g. angiotensin II, insulin, thyroid hormones, etc) may significantly contribute to the development of the cardiac structural alterations frequently detected in the clinical course of the hypertensive state2,3.

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Author information

Authors and Affiliations

  1. Cattedra di Medicina Interna I, Ospedale S. Gerardo, Monza, Italy

    Dr. Guido Grassi & Giuseppe Mancia

  2. Centro di Fisiologia Clinica e Ipertensione Ospedale Maggiore, IRCCS, Università di Milano, Milano, Italy

    Dr. Guido Grassi, Gino Seravalle & Giuseppe Mancia

  3. IRCCS, Centro Auxologico Italiano, Milano, Italy

    Gino Seravalle & Giuseppe Mancia

Authors
  1. Dr. Guido Grassi
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  2. Gino Seravalle
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  3. Giuseppe Mancia
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Editor information

Editors and Affiliations

  1. University of Milan, Milan, Italy

    Alberto Zanchetti

  2. Cornell University Medical College, New York, New York, USA

    Richard B. Devereux

  3. University of Uppsala, Uppsala, Sweden

    Lennart Hansson

  4. International Menarini Foundation, Milan, Italy

    Sergio Gorini

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© 1997 Springer Science+Business Media New York

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Grassi, G., Seravalle, G., Mancia, G. (1997). Left Ventricular Hypertrophy and Sympathetic Activity. In: Zanchetti, A., Devereux, R.B., Hansson, L., Gorini, S. (eds) Hypertension and the Heart. Advances in Experimental Medicine and Biology, vol 432. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-5385-4_18

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  • DOI: https://doi.org/10.1007/978-1-4615-5385-4_18

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-7458-9

  • Online ISBN: 978-1-4615-5385-4

  • eBook Packages: Springer Book Archive

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