Carbohydrate Recognition Systems in Innate Immunity

  • Ten Feizi
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 435)


Carbohydrate-protein interactions have emerged as important recognition systems in the orchestration of mechanisms of innate immunity1. Unlike the usual situation of receptor-ligand pairs2, a picture is emerging of recognition systems that operate as triads: receptors, ligands and carriers. Here the receptors are lectins3, the ligands are oligosaccharides, and when they are optimally assembled on carriers (proteins or lipids) functional counter-receptors are formed, as depicted in Figure 1.


Recognition System Carbohydrate Ligand Sulfated Oligosaccharide Imperial College School Carbohydrate Binding Activity 
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Copyright information

© Springer Science+Business Media New York 1998

Authors and Affiliations

  • Ten Feizi
    • 1
  1. 1.The Glycosciences Laboratory Imperial College School of MedicineNorthwick Park HospitalHarrowUK

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