Abstract
Regarding the involvement of kindling in clinical epilepsy (Table 1) as reviewed previously [1], the discussion herein is focused on two issues: the neuromechanisms of repeated brief seizures (RBS)-induced epileptogenesis and the neuropharmacology of antiepileptics. The former is related to the refractoriness in some types of epilepsy, and the latter may be important to the developent of new antiepileptics able to alleviate the epileptic disorders of Engel [2]. Results of our recent studies on these central problems of epilepsy are presented.
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Morimoto, K., Sato, H., Osawa, M., Sato, M. (1998). Contributions of Kindling to Clinical Epileptology. In: Corcoran, M.E., Moshé, S.L. (eds) Kindling 5. Advances in Behavioral Biology, vol 48. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-5375-5_34
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DOI: https://doi.org/10.1007/978-1-4615-5375-5_34
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