Abstract
One of the pressing questions in pediatric epilepsy is whether seizures cause brain damage. Determining the relative contribution of variables such as seizure type, frequency, duration, age of onset, etiology, and drug effects makes it difficult to assess the role of seizures per se in neurological sequelae. Because of the inherent difficulties in determining the effects of seizures using clinical data, animal models can provide insights into the mechanism of seizure-induced damage.
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Sarkisian, M., Tandon, P., Holmes, G.L. (1998). Long-Term Effects of Kindling on Learning and Memory in the Developing Brain. In: Corcoran, M.E., Moshé, S.L. (eds) Kindling 5. Advances in Behavioral Biology, vol 48. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-5375-5_3
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DOI: https://doi.org/10.1007/978-1-4615-5375-5_3
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