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Kindling 5 pp 327–348Cite as

Amygdala Kindling and Rodent Anxiety

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Part of the book series: Advances in Behavioral Biology ((ABBI,volume 48))

Abstract

Kindling of the mammalian limbic system has been suggested as a model of epileptogenesis in complex partial seizure disorder2 (CPS). The most commonly agreed upon problems of an affective nature associated with epilepsy are anxiety and depression2,42,87. An extensive literature implicates the amygdala in the production of fearful and anxiety related states in animals and humans. It is of interest, then, that anterior temporal lobectomy in human epileptics resecting the amygdala and the anterior hippocampus reduces a preexisting anxiety disorder43. Data like these, and a great deal of other data1, implicate alteration of amygdala functioning in affective disturbance in epilepsy.

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Authors and Affiliations

  1. Department of Psychology, Memorial University of Newfoundland, 232 Elizabeth Avenue, St. John’s, Newfoundland, A1B 3X9, Canada

    Robert Adamec

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  1. Robert Adamec
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  1. University of Saskatchewan, Saskatoon, Saskatchewan, Canada

    Michael E. Corcoran

  2. Albert Einstein College of Medicine, Bronx, New York, USA

    Solomon L. Moshé

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Adamec, R. (1998). Amygdala Kindling and Rodent Anxiety. In: Corcoran, M.E., Moshé, S.L. (eds) Kindling 5. Advances in Behavioral Biology, vol 48. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-5375-5_24

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  • DOI: https://doi.org/10.1007/978-1-4615-5375-5_24

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