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Abstract

Occlusion of the lacrimal drainage system has been advocated in cases of dry eye where other forms of treatment including artificial tears and lid hygiene have proved inadequate. The first method of occlusion suggested was cautery of the tissue around the canaliculus and punctum to prevent tear drainage.1 The first temporary occlusion technique was described in the city of Glasgow by Foulds2 in 1961 who advocated the use of gelatin implants. Today collagen plugs are commercially available (Eagle Vision, Memphis, TN; Lacrimedics, Rialto, CA) to temporarily block tear drainage. The efficacy of dissolvable collagen in blocking punctal drainage is less than complete.3–5 Lowther and Semes5 found that collagen plugs had no appreciable effect on tear break-up, tear prism height, fluorescein, or rose bengal staining, yet patients reported that dryness-related symptoms were significantly reduced.

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References

  1. Beetham WP. Filimentary keratitis. Trans Am Ophthalmol Soc. 1935; 33: 413–435.

    PubMed  CAS  Google Scholar 

  2. Foulds WS. Intracannicular gelatin implants in the treatment of kerateconjunctivitis sicca. Br J Ophthalmol. 1961; 45: 625–627.

    Article  PubMed  CAS  Google Scholar 

  3. Groves SW, Forstat SL, Lear J. Intracannicular collagen implants: A dacryoscintigraphy study. Invest Ophthalmol Vis Sci. 1991: 32: 727.

    Google Scholar 

  4. Apte RV. Quantitative analysis of tear outflow reduction due to intracannicular collagen implants using lacrimal scintillography. Invest Ophthalmol Vis Sci. 1994; 35: 1692.

    Google Scholar 

  5. Lowther GE, Semes L. Effective of absorbable intracannicular collagen implants in hydrogel contact lens patients with drying symptoms. International Contact Lens Clinic. 1995; 22: 238–243.

    Google Scholar 

  6. Freeman JM. The Punctum Plug: Evaluation of a new treatment for the dry eye. Trans Am Acad Ophthalmol Otolaryngol. 1973; 79: 874–879.

    Google Scholar 

  7. Slusser TG. A review of hydrogel contact lens-related dry eye and lacrimal drainage occlusiion. International Contact Lens Clinic. 1995; 22: 250–254.

    Google Scholar 

  8. Dolhman CH. Punctal occlusion in keratoconjunctivitis sicca. Ophthalmology. 1978; 85: 1277–1281.

    Google Scholar 

  9. Gilbard J. Tear film osmolarity in keratoconjunctivitis sicca. CLAO J. 1985; 11: 243–250.

    PubMed  CAS  Google Scholar 

  10. Gilbard J, Rossi SR, Azar DT, Heyda KJ. Effective punctal occlusion by Freeman silicone plug insertion on tear osmolality in dry eye disorders. CLAO J. 1989; 15: 216–218.

    PubMed  CAS  Google Scholar 

  11. Tsubota K, Yamada M. Tear evaporation from the ocular surface. Invest Ophthalmol Vis Sci. 1992; 33: 2943–2950.

    Google Scholar 

  12. Tomlinson A, Craig JP, Lowther GE. The biophysical role in tear regulation. (This volume).

    Google Scholar 

  13. Willis RM, Folberg R, Krachmer JH, Holland EJ. The treatment of aqueous deficient dry eye with removable punctal plugs. Ophthalmology. 1987; 94: 514–518.

    PubMed  CAS  Google Scholar 

  14. Giovagnoli D, Graham S. Inferior punctal occlusion with the removable silicone punctal plugs in the treatment of dry eye related contact lens discomfort. J Am Optom Assoc. 1992; 63: 481–485.

    PubMed  CAS  Google Scholar 

  15. Slusser TG. Effects of lacrimal drainage occlusion with non dissolvable intracannicular plugs on hydrogel contact lens related dry eye. Thesis, University of Alabama at Birmingham, Birmingham, AL, 1984.

    Google Scholar 

  16. Fullard RJ, Tucker DL. Changes in human tear protein-levels with progressively increasing stimulus. Invest Ophthalmol Vis Sci. 1991; 32: 2290–2301.

    PubMed  CAS  Google Scholar 

  17. Boonstra A, Kijlstra A. Separation of human tear proteins by high-performance liquid chromatography. Curr Eye Res. 1984; 3: 1461–1469.

    Article  PubMed  CAS  Google Scholar 

  18. Hamdi HK, Berjis F, Brown DJ, Kenney MC. Proteinase activity in normal human tears - male-female dimorphism. Curr Eye Res. 1995; 14: 1081–1086.

    Article  Google Scholar 

  19. Occhipinti JR, Mosier MA, LaMotte J, Monji GT. Fluorophotometric measurement of human tear turnover rate. Curr Eye Res. 1988; 7: 995–1000.

    Article  PubMed  CAS  Google Scholar 

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© 1998 Springer Science+Business Media New York

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Pearce, E.I., Tomlinson, A., Craig, J.P., Lowther, G.E. (1998). Tear Protein Levels Following Punctal Plugging. In: Sullivan, D.A., Dartt, D.A., Meneray, M.A. (eds) Lacrimal Gland, Tear Film, and Dry Eye Syndromes 2. Advances in Experimental Medicine and Biology, vol 438. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-5359-5_95

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  • DOI: https://doi.org/10.1007/978-1-4615-5359-5_95

  • Publisher Name: Springer, Boston, MA

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