Abstract
Graft rejection is defined as a permanent loss of the original function of the transplanted tissue or organ, caused by immunological reactions. In case of corneal transplantation, this is not a literal rejection but edema formation, which is followed by invasion of the transplant by host leukocytes, vascularization of the otherwise avascular cornea, and scar formation. In case of transplanted corneas, the permenant loss of transparency due to scarring constitutes the change that makes possible the use of the term transplant rejection.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
Similar content being viewed by others
References
Polack FM. The corneal graft reaction: An immunological, pathological and clinical perspective. In: Immunology of the Eye. Workshop I. Washington, DC. Information Retrieval; 1981: 207–219.
Alberth B. Keratoplastik. Stuttgart: Enke Verlag, 1961; 125–146.
Berta A. Allergic and Immunological Diseases of the Eye. In: Berta A. Enzymology of the tears. Boca Raton: CRC Press; 1992: 233–242.
Chandler JW, Leder R, Kaufman HE, Caldwell JR. Quantitative determinations of complement components and immunoglobulins in tears and aqueous humor. Invest Ophthalmol. 1974; 13: 151–157.
Berta A. Significance of tear protein tests in the prediction of corneal graft rejection. (in Hungarian) Szemészet. 1985; 122: 172–177.
Zajácz M, Berta A. Proteolytische Enzymaktivitat and chirurgische Eingriffe bei Ulcus Mooren. KIM Monatsbl Augenheilkd. 1985; 187: 401–402.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1998 Springer Science+Business Media New York
About this chapter
Cite this chapter
Berta, A., Lampé, Z. (1998). Immunoglobulin Levels in the Tears of Patients with Corneal Grafts and Transplant Rejection. In: Sullivan, D.A., Dartt, D.A., Meneray, M.A. (eds) Lacrimal Gland, Tear Film, and Dry Eye Syndromes 2. Advances in Experimental Medicine and Biology, vol 438. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-5359-5_85
Download citation
DOI: https://doi.org/10.1007/978-1-4615-5359-5_85
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4613-7445-9
Online ISBN: 978-1-4615-5359-5
eBook Packages: Springer Book Archive