Skip to main content
SpringerLink
Log in

Volume of the Human and Rabbit Meibomian Gland System

  • Chapter
Lacrimal Gland, Tear Film, and Dry Eye Syndromes 2

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 438))

Abstract

Meibomian gland secretion (meibom) in human1–5 and rabbit6,7 comprises triglycerides, neutral lipids, and polar lipids. Phospholipids have been further identified and quantified.8 Collectively, these lipids are believed to form the lipid layer of the tear film, which can be observed in the interpalpebral fissure by interferometry.9–11

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Tiffany JM. Individual variations in human meibomian lipid composition. Exp Eye Res. 1978; 27: 289–300.

    Article  PubMed  CAS  Google Scholar 

  2. Nicolaides N, Kataranta JKJ, Rawdah TN, Macy JI, Boswell FM III, Smith RE. Meibomian gland studies: Composition of steer and human lipids. Invest Ophthalmol Vs Sci. 1981; 20: 522–536.

    CAS  Google Scholar 

  3. Nicolaides N, Ruth EC. Unusual fatty acids in the lipids of steer and human meibomian gland excreta. Curr Eye Res. 1982; 2: 93–98.

    Article  PubMed  Google Scholar 

  4. Nicolaides N, Santos EC, Papadakis K. Double-bond patterns of fatty acids and alcohols in steer and human meibomian gland lipids. Lipids 1984; 19: 264–277.

    Article  PubMed  CAS  Google Scholar 

  5. Nicolaides N, Santos EC. The di-and triesters of the lipids of steer and human meibomian glands. Lipids. 1985; 20: 454–467.

    Article  PubMed  CAS  Google Scholar 

  6. Tiffany JM. The meibomian lipids of the rabbit. I. Overall composition. Exp Eye Res. 1979; 29: 195–202.

    Article  PubMed  CAS  Google Scholar 

  7. Tiffany JM, Marsden RG. The meibomian lipids of the rabbit. II. Detailed composition of the principal esters. Exp Eye Res. 1982; 34: 601–608.

    Article  PubMed  CAS  Google Scholar 

  8. Greiner JV, Glonek T, Korb DR, Booth R, Leahy CD. Phospholipid profile of meibomian gland secretion: A phosphorus-31 nuclear magnetic resonance spectroscopic study. Ophthalmic Res. 1996; 28: 44–49.

    Article  PubMed  CAS  Google Scholar 

  9. Korb DR, Greiner.1V. Increase in tear film lipid layer thickness following treatment of meibomian gland dysfunction. Adv Exp Med Biol. 1994; 350: 293–298.

    Article  PubMed  CAS  Google Scholar 

  10. Korb DR, Baron DF, Herman JP, et al. Tear film lipid layer thickness as a function of blinking. Cornea. 1994; 13: 354–359.

    Article  PubMed  CAS  Google Scholar 

  11. Korb DR, Greiner JV, Glonek T, Esbah R, Finnemore VM, Whalen AC. Effect of periocular humidity on the tear film lipid layer. Cornea. 1996; 15: 129–134.

    Article  PubMed  CAS  Google Scholar 

  12. Ekins MB, Waring GO. Absent meibomian glands and decreased corneal sensation in hydrotic ectodermal dysplasia. J Pediatr Ophthalmol Strabismus. 1981; 18: 44–47.

    PubMed  CAS  Google Scholar 

  13. Mondino BJ, Bath PE, Foos BV. Absent meibomian glands in the ectodactyl, ectodermal dysplasia and cleft lip-palate syndrome. Am J Ophthalmol. 1984; 97: 496–500.

    PubMed  CAS  Google Scholar 

  14. Bron AJ, Mengher GO. Congenital deficiency of meibomian glands. Br J Ophthalmol. 1987; 71: 312–314.

    Article  PubMed  CAS  Google Scholar 

  15. Korb DR Greiner JV, Glonek T, et al. Human and rabbit lipid layer and interference pattern observations. This volume.

    Google Scholar 

  16. Hykin PG, Bron AJ. Age-related morphological changes in lid margin and meibomian gland anatomy. Cornea. 1992; 11: 334–342.

    Article  PubMed  CAS  Google Scholar 

  17. Prince JH, ed. The Rabbit in Eye Research. Springfield, IL: Charles C. Thomas;1964, p 50.

    Google Scholar 

  18. Cogan DG, Fink R, Donaldson DD. X-ray irradiation of orbital glands of rabbit. Radiology. 1955; 64: 731–737.

    PubMed  CAS  Google Scholar 

  19. Paule WJ. The Comparative Histochemistry of the Harderian Gland. Ohio State University, 1957.

    Google Scholar 

  20. Schneir ES, Hayes ER. The histochemistry of the Harderian gland of the rabbit. Natl Cancer Inst J. 1951; 12: 257.

    Google Scholar 

  21. Walter A. Ueber die HautderÂsen mit Lipoidsekretion bei Nagern. Bietr. path. Anat. Path. 1924; 73: 142–167.

    Google Scholar 

  22. Greiner JV, Glonek T, Korb DR, Leahy CD. Meibomian gland phospholipids. Curr Eye Res. 1996; 15: 371–375.

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Schepens Eye Research Institute, Harvard Medical School, Boston, Massachusetts, USA

    Jack V. Greiner, Stacey L. Hearn & Charles D. Leahy

  2. Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts, USA

    Jack V. Greiner

  3. MR Laboratory, Midwestern University, Chicago, Illinois, USA

    Thomas Glonek

  4. 100 Boylston Street, Boston, Massachusetts, USA

    Donald R. Korb, Amy C. Whalen, Eric Hebert & Jan E. Esway

Authors
  1. Jack V. Greiner
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Thomas Glonek
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Donald R. Korb
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Amy C. Whalen
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Eric Hebert
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Stacey L. Hearn
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. Jan E. Esway
    View author publications

    You can also search for this author in PubMed Google Scholar

  8. Charles D. Leahy
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. The Schepens Eye Research Institute, Harvard Medical School, Boston, Massachusetts, USA

    David A. Sullivan  & Darlene A. Dartt  & 

  2. Louisiana State University Medical Center, New Orleans, Louisiana, USA

    Michele A. Meneray

Rights and permissions

Reprints and permissions

Copyright information

© 1998 Springer Science+Business Media New York

About this chapter

Cite this chapter

Greiner, J.V. et al. (1998). Volume of the Human and Rabbit Meibomian Gland System. In: Sullivan, D.A., Dartt, D.A., Meneray, M.A. (eds) Lacrimal Gland, Tear Film, and Dry Eye Syndromes 2. Advances in Experimental Medicine and Biology, vol 438. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-5359-5_48

Download citation

  • DOI: https://doi.org/10.1007/978-1-4615-5359-5_48

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-7445-9

  • Online ISBN: 978-1-4615-5359-5

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation