Abstract
One manifestation of dry eye is a reduction in tear volume. In mammals, much of the tear volume is thought to arise from the acinar secretory and duct cells of the lacrimal gland. The subjacent tissue of the gland contains reticular-like connective tissue with scattered lymphocytes. Plasma cells within the connective tissue produce IgA, which is sequestered intracellularly by acinar cells and processed and finally secreted into the lumen of the gland.1 Many other secretory products are generated by the acinar cells. Secretagogue-triggered vesicle release is the process used by acinar cells to secrete proteins.
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Brink, P.R., Peterson, E., Banach, K., Walcott, B. (1998). Electrophysiological Evidence for Reduced Water Flow from Lacrimal Gland Acinar Epithelium of NZB/NFW F1 Mice. In: Sullivan, D.A., Dartt, D.A., Meneray, M.A. (eds) Lacrimal Gland, Tear Film, and Dry Eye Syndromes 2. Advances in Experimental Medicine and Biology, vol 438. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-5359-5_31
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DOI: https://doi.org/10.1007/978-1-4615-5359-5_31
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