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Oral Pilocarpine for Symptomatic Relief of Keratoconjunctivitis Sicca in Patients with Sjögren’s Syndrome

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Lacrimal Gland, Tear Film, and Dry Eye Syndromes 2

Abstract

Sjogren’s syndrome (SS) was first described by Henrik Sjögren, who documented association of rheumatoid arthritis and systemic immunopathy characterized by symptoms of dryness, especially KCS and xerostomia.

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References

  1. Fox RI. Vth International Symposium on Sjögren’s Syndrome: Clinical aspects and therapy. Clin Rheumatol. 1995; 14 (Suppl.l): 17–19.

    PubMed  Google Scholar 

  2. Fox RI, Robinson CA, Curd JG, et al. Sjögren’s syndrome: Proposed criteria for classification. Arthritis Rheum. 1986; 29: 577–585.

    Article  PubMed  CAS  Google Scholar 

  3. Lemp MA. Report of the National Eye Institute/Industry Workshop on Clinical Trials in Dry Eyes. CLAO J. 1995; 21: 221–232.

    PubMed  CAS  Google Scholar 

  4. Oxholm P, Asmussen K. Classification of disease manifestations in primary Sjögren’s syndrome: Present status and a new proposal. Clin Rheumatol. 1995; 14 (Suppl. l): 3–7.

    PubMed  Google Scholar 

  5. Lemp MA. Management of the dry-eye patient. Int Ophthalmol Clin. 1994; 34 (1): 101–113.

    Article  PubMed  CAS  Google Scholar 

  6. Fox RI, Izuno G, Simon RA, et al. Sjögren’s Syndrome: A Guide for the Patients. National Sjögren’s Syndrome Association. 1990: 2–30.

    Google Scholar 

  7. Nelson JD. Dry eye: Etiology, diagnosis, and management.“ Pharmacy Times. 1996 September;66–78.

    Google Scholar 

  8. Moutsopoulos HM. Sjögren’s syndrome. In: Isselbacher KJ, Braunwald E, Wilson JD., et al., eds. Harrison Principles of Internal Medicine, 12th ed. New York: McGraw-Hill; 1991; 1449–1450.

    Google Scholar 

  9. LeVeque FG, Montgomery M, Potter D, et al. A multicenter, randomized, double-blind, placebo-controlled, dose-titration study of oral pilocarpine for treatment of radiation-induced xerostomia in head and neck cancer patients. J Clin Oncol. 1993; 11: 1124–1131.

    PubMed  CAS  Google Scholar 

  10. Johnson JT, Ferretti GA, Nethery WJ, et al. Oral pilocarpine for post-radiation xerostomia in patients with head and neck cancer. N Engl J Med. 1993; 329: 390–395.

    Article  PubMed  CAS  Google Scholar 

  11. Rieke JW, Hafermann MD, Johnson IT, et al. Oral pilocarpine for radiation-induced xerostomia: Integrated efficacy and safety results from two prospective randomized clinical trials. Int J Radiat Oncol Biol Phys. 1995; 31: 661–669.

    Article  PubMed  CAS  Google Scholar 

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© 1998 Springer Science+Business Media New York

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Nelson, J.D. et al. (1998). Oral Pilocarpine for Symptomatic Relief of Keratoconjunctivitis Sicca in Patients with Sjögren’s Syndrome. In: Sullivan, D.A., Dartt, D.A., Meneray, M.A. (eds) Lacrimal Gland, Tear Film, and Dry Eye Syndromes 2. Advances in Experimental Medicine and Biology, vol 438. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-5359-5_140

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  • DOI: https://doi.org/10.1007/978-1-4615-5359-5_140

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-7445-9

  • Online ISBN: 978-1-4615-5359-5

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