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Immune Control of HIV-1 Replication

  • Chapter
Mechanisms of Lymphocyte Activation and Immune Regulation VII

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 452))

Abstract

Over 30 million persons are infected with HIV-1 worldwide, and over 8000 new infections occur every day1. Although there have been enormous advances in antiretroviral therapy against this retrovirus, economic constraints mean that over 90% of infected persons will never benefit from these therapies. The only solution for the global epidemic is the development of an effective vaccine. Such development is predicated on the assumption that this virus can be contained by immune responses. Recent evidence now supports the contention that effective immunity can be generated in natural infection, and this provides encouragement for accelerated vaccine efforts.

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Author information

Authors and Affiliations

  1. Partners AIDS Research Center and Infectious Disease Division, Massachusetts General Hospital and Harvard Medical School, 149 13th Street, Charlestown, Massachusetts, 02129, USA

    Bruce D. Walker, Eric S. Rosenberg, Christine M. Hay, Nesli Basgoz & Otto O. Yang

Authors
  1. Bruce D. Walker
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  2. Eric S. Rosenberg
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  3. Christine M. Hay
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  4. Nesli Basgoz
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  5. Otto O. Yang
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Corresponding author

Correspondence to Bruce D. Walker .

Editor information

Editors and Affiliations

  1. University of California, Irvine, Irvine, California, USA

    Sudhir Gupta

  2. National Institutes of Health, Bethesda, Maryland, USA

    Alan Sher

  3. Emory University, Atlanta, Georgia, USA

    Rafi Ahmed

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© 1998 Springer Science+Business Media New York

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Walker, B.D., Rosenberg, E.S., Hay, C.M., Basgoz, N., Yang, O.O. (1998). Immune Control of HIV-1 Replication. In: Gupta, S., Sher, A., Ahmed, R. (eds) Mechanisms of Lymphocyte Activation and Immune Regulation VII. Advances in Experimental Medicine and Biology, vol 452. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-5355-7_17

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  • DOI: https://doi.org/10.1007/978-1-4615-5355-7_17

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-7443-5

  • Online ISBN: 978-1-4615-5355-7

  • eBook Packages: Springer Book Archive

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