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Retinal Ganglion Cell Axonal Transport

Moving down the Road to Functional Connections

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Book cover Development and Organization of the Retina

Part of the book series: NATO ASI Series ((NSSA,volume 299))

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Abstract

Retinal ganglion cells form the essential link between the eye and the brain, conveying visual information transduced at the retina for further visual processing in higher centers. In visual animals, this pathway is marked by a high order of functional and anatomical organization. Developmental studies are one approach aimed at understanding how global connectivity and the specificity of the primary visual projection is established. Since the formation of retinofugal pathways follows the general program of developmental events in the brain, developmental studies of this pathway also shed light on the formation of the neuronal network in general. A highly simplified view of the major developmental events in the nervous system would start with the generation of neuronal precursors, followed by neuronal differentiation which in the case of long projection neurons involves rapid axon outgrowth over considerable distances, the formation of synaptic relationships, and finally the efficient processing of neuronal signals along the neural network. The method described below is particularly adapted for studies of neuronal protein changes during the latter three stages of development.

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Author information

Authors and Affiliations

  1. CNRS URA 2210 and INSERM U334, SHFJ, DRM, CEA, Orsay, France

    Kenneth L. Moya

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  1. Kenneth L. Moya
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Editors and Affiliations

  1. University of California at Davis, Davis, California, USA

    Leo M. Chalupa

  2. Cornell University, Ithaca, New York, USA

    Barbara L. Finlay

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© 1998 Springer Science+Business Media New York

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Moya, K.L. (1998). Retinal Ganglion Cell Axonal Transport. In: Chalupa, L.M., Finlay, B.L. (eds) Development and Organization of the Retina. NATO ASI Series, vol 299. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-5333-5_14

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  • DOI: https://doi.org/10.1007/978-1-4615-5333-5_14

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-7433-6

  • Online ISBN: 978-1-4615-5333-5

  • eBook Packages: Springer Book Archive

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