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Effects of Growth Hormone on Muscle Mass and Function

  • Chapter
Book cover Growth Hormone

Part of the book series: Endocrine Updates ((ENDO,volume 4))

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Abstract

The anabolic nature of growth hormone (GH) is dramatically exhibited by patients with acromegaly, and indirectly by patients with GH-deficiency. A large number of in vitro and animal studies for several decades has documented stimulating effects of GH on skeletal muscle growth (1). The methods employed to document in vivo effects of GH on muscle mass in humans have been exhaustive including whole body retention of nitrogen and potassium, total and regional muscle protein metabolism using labeled amino acids, estimation of lean body mass by total body potassium or dual x-ray absorptiometry (DEXA), and direct calcualtion of muscle area or volume by computerised tomography (CT) and magnetic resonance imaging (MRI).

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Authors and Affiliations

  1. Medical Department M (Endocrinology and diabetes), Aarhus University Hospital, Aarhus, Denmark

    Jens Otto Lunde Jørgensen, Rolf Dall, Nina Vahl, Helene Nørrelund & Jens Sandahl Christiansen

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  1. Jens Otto Lunde Jørgensen
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  2. Rolf Dall
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  3. Nina Vahl
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  4. Helene Nørrelund
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  5. Jens Sandahl Christiansen
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Editors and Affiliations

  1. Sahlgrenska University Hospital, Göteborg, Sweden

    Bengt-Åke Bengtsson M.D.

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© 1999 Springer Science+Business Media New York

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Jørgensen, J.O.L., Dall, R., Vahl, N., Nørrelund, H., Christiansen, J.S. (1999). Effects of Growth Hormone on Muscle Mass and Function. In: Bengtsson, BÅ. (eds) Growth Hormone. Endocrine Updates, vol 4. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-5163-8_14

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  • DOI: https://doi.org/10.1007/978-1-4615-5163-8_14

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-7351-3

  • Online ISBN: 978-1-4615-5163-8

  • eBook Packages: Springer Book Archive

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