Abstract
Viral pathogenesis is the mechanism by which viruses enter host plants, establish infection, and cause disease. It encompasses several events such as entry into the host by being deposited in a cell by viral vectors such as insects, nematodes etc. that feed on host plants or by mechanical damage to cell wall and plasma membrane. It is followed by replication and assembly of the daughter virus particles at the specific site(s), spread from the site of infection to neighboring healthy cells (cell-to-cell movement) followed by invasion of distal parts of the plant (long-distance movement) (Chapter 7), and disease induction during which specific symptoms are produced.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Bancroft, J. B. (1972). A virus made from parts of the genomes of brome mosaic and cowpea chlorotic mottle viruses. J. Gen. Virol. 14, 223–228.
Bancroft, J. B., and Lane, L. (1973). Genetic analysis of cowpea chlorotic mottle and brome mosaic viruses.J. Gen. Virol. 19, 381–389.
Banerjee, N., Wang, J. Y., and Zaitlin, M. (1995). A single nucleotide change in the coat protein gene of tobacco mosaic virus is involved in the induction of severe chlorosis. Virology 207, 234–239.
Cronin, S., Verchot, J., Haldeman-Cahil, R., Schaad, M. C., and Carrington, J. C. (1995). Long distance movement factor: A transport function of the potyvirus helper component proteinase. Plant J. 7, 549–559.
Culver, J. N., and Dawson, W. O. (1989). Tobacco mosaic virus coat protein: An elicitor of the hypersensitive reaction but not required for the development of mosaic symptoms in Nicotiana sylvestris. Virology 173, 755–758.
Culver, J. N., and Dawson, W. O. (1991). Tobacco mosaic virus elicitor coat protein genes produce hypersensitive phenotype in transgenic Nicotiana sylvestris. Mol. Plant-Microbe Interact. 2, 209–213.
Culver, J. N., Lindbeck, A. G. C., and Dawson, W. O. (1991). Virus-host interactions: Identitiation of chlorotic and necrotic responses in plants by tobamoviruses. Annu. Rev. Phytopathol. 29, 193–217.
Culver, J. N., Stubbs, G., and Dawson, W. O. (1994). Structure-function relationship between tobacco mosaic virus coat protein and hypersensitivity in Nicotiana sylvestris. J Mol. Biol. 242, 130–138.
Dawson, W. O. (1992). Tobamovirus-plant interactions. Virology 186, 359–367.
Dawson, W. O., Bubrick, P., and Grantham, G. (1988). Modifications of the tobacco mosaic virus coat protein gene affecting replication, movement and symptomatology. Phytopathology 78, 783–789.
Deom, C. M., Lapidot, M., Beachy, R. N. (1992). Plant virus movement proteins. Cell 69, 221–224.
Edwards, M. C., Gonsalves, D., and Provvidenti, R. (1982). Genetic analysis of cucumber mosaic virus in relation to host resistance: Location of determinants for pathogenicity to certain legumes and Lactuca saligna. Phytopathology 73, 269–273.
Flasinski, S., Dzianott, A., Pratt, S., and Bujarski, J. (1995). Mutational analysis of the coat protein gene of brome mosaic virus: Effects on replication and movement in barley and in Chenopodium hybridum. Mol. Plant-Microbe Interact. 8, 23–31.
Fujita, Y., Mise, K., Okuno, T., Ahlquist, P., and Furusawa, I. (1996). A single codon change in a conserved motif of a bromovirus movement protein gene confers compatibility with a new host. Virology 223, 283–291.
Gal-On, A., Kaplan, I., Roossinck., M. J., and Palukaitis, P. (1994). The kinetics of infection of zucchini squash by cucumber mosaic virus indicates a function for RNAI in virus movement. Virology 205, 280–289.
Habili, N., and Francki, R. I. B. (1974). Comparative studies on tomato aspermy and cucumber mosaic viruses. III. Further studies on relationship and construction of a virus from parts of the two viral genomes. Virology 61, 443–449.
Harrison, B. D., Murant, A. F., Mayo, M. A., and Roberts, I. M. (1974). Distribution of determinants symptom production, host range and nematode transmissibility between the two RNA components of raspberry ringspot virus. J. Gen. Virol. 22, 233–247.
Heaton, L. A., and Laakso, M. M. (1995). Several symptom modulating mutations in the coat protein turnip crinkle carmovirus result in the particle with aberrant conformational properties. J. Gen. Virol. 76, 225–230.
Heaton, L. A., Lee, T. C., Wei, N., and Morris, T. J. (1991). Point mutations in the turnip crinkle virus capsid protein affect the symptoms expressed by Nicotiana benthamiana. Virology 183, 143–150.
Kong, Q., Oh, J. W., Carpenter, C. D., and Simon, A. E. (1997). The coat protein of turnip crinkle virus is involved in subviral RNA-mediated symptom modulation and accumulation. Virology 238, 478–485.
Kasteel, D. T. J., Van der Wel N., Jansen, K. A. J., Goldbach, R. W., and Van Lent, J. W. M. (1997). Tubule-forming capacity of the movement proteins of alfalfa mosaic virus and brome mosaic virus. J.Gen. Virol. 78, 2089–2093.
Keen, N. T. (1990). Gene-for-gene complementary in plant pathogens and symbionts. Annu. Rev. Genet. 24, 447–463.
Knorr, D. A. and Dawson, W. 0. (1988). A point mutation in the tobacco mosaic virus capsid protein gene induces hypersensitivity in Nicotiana sylvestris. Proc. Natl. Acda. Sci. USA 85, 170–174.
Lewandowski, D. J and Dawson, W. 0. (1993). A single amino acid change in tobacco mosaic virus replicase prevents symptom production. Mol. Plant Microbe. Interact. 6, 157–160.
Mise, K. and Ahlquist, P. (1995). Host specificity restriction by bromovirus cell-to-cell movement protein occurs after initial cell-to-cell spread of infection in nonhost plants. Virology 206, 276–286.
Mise, K., Allison, R. F., Janda, M., and Ahlquist, P. (1993). Bromovirus movement protein genes play a crucial role in host specificity. J. Virol. 67, 2815–2823.
Mossop, D. W., and Francki, R. 1. B. (1977). Association of RNA3 with aphid transmission of cucumber mosaic virus. Virology 81, 177–181.
Mossop, D. W., Francki, R. I. B., and Grivell, C. J. (1976). Comparative studies on tomato aspermy and cucumber mosaic viruses. V. Purification and properties of a cucumber mosaic virus inducing severe chlorosis. Virology 74, 544–546.
Oh, J. W., Kong, Q., Song, S., Carpenter, C. D., Simon. A. E. (1995). Open reading frames of turnip crinkle virus involved in satellite symptom expression and incompatibility with Arabidopsis thalianas ecotype Dijon. Mol. Plant-Microbe Interact. 8, 979–987.
Osman, F., Grantham, G. L., and Rao, A. L. N. (1997). Molecular studies on bromovirus capsid protein. IV. Coat protein exchanges between brome mosaic and cowpea chlorotic mottle viruses exhibit neutral effects in heterologous hosts. Virology 238, 452–459.
Palukaitis, P., Roossnick, M. J., Shintaku, M. H., and Sleat, D. E. (1991). Mapping functional domains in cucumber mosaic virus and its satellite RNAs. Can. J. Plant Pathol. 13, 155–162.
Rao, A. L. N. (1997). Molecular studies on bromovirus capsid protein: III. Analysis of cellto-cell movement competence of coat protein defective variants of cowpea chlorotic mottle virus. Virology, 385–395.
Rao, A. L. N. and Francki, R. I. B. (1981). Comparative studies on tomato aspermy and cucumber mosaic viruses. VI. Partial compatibility of genome segments from the two viruses. Virology 114, 573–575.
Rao, A. L. N. and Francki, R. I. B. (1982). Distribution of determinant for symptom production and host range on the three RNA components of cucumber mosaic virus. J. Gen. Virol. 61, 197–205.
Rao, A. L. N. and Hiruki, C. (1987). Unilateral compatibility of genome segments from two distinct strains of red clover necrotic mosaic virus. J. Gen. Virol. 68, 191–194.
Rao, A. L. N., and Grantham, G. L. (1995a). A spontaneous mutation in the movement protein gene of brome mosaic virus modulates symptom phenotype in Nicotiana benthamiana. J. Virol. 69, 2689–2691.
Rao, A. L. N., and Grantham, G. L. (1995b). Biologica I significance of the seven amino-terminal basic residues of brome mosaic virus coat protein. Virology 211, 42–52.
Rao, A. L. N., and Grantham, G. L. (1996). Molecular studies on bromovirus capsid protein: I1. Functional analysis of the amino terminal arginine rich motif and its role in encapsidation, movement and pathology. Virology 226, 294–305.
Rao, A. L. N., Sullavan, B., and Hall, T. C (1990). Use of Chenopodium hybridum facilitates isolation of brome mosaic virus RNA recombinants. J. Gen. Virol. 71, 1403–1407.
Roossnick, M. J., and Palukaitis, P. (1990). Rapid induction and severity of symptoms in zucchini squash (Cucurbita pepo) map to RNAI of cucumber mosaic virus. Mol. Plant-Microbe Interact. 3, 188–192.
Routh, G., Dodds, A. J., Fitzmaurice, L., and Mirkov, T. E. (1995). Characterization of deletion and frameshift mutants of satellite tobacco mosaic virus. Virology 212, 121–127.
Sacher, R., and Ahlquist, P. (1989). Effects of deletions in the N-terminal basic arm of brome mosaic virus coat protein on RNA packaging and systemic infection. J Virol. 63, 4545–4552.
Schmitz, I., and Rao, A. L. N. (1996). Molecular studies on bromovirus capsid protein. I. Characterization of cell-to-cell movement-defective RNA3 variants of brome mosaic virus. Virology 226, 281–293.
Schmitz, I., and Rao, A. L. N. (1998). Deletions in the conserved amino-terminal basic arm of cucumber mosaic virus coat protein disrupt virion assembly but do not abolish infectivity and cell-to-cell movement. Virology 248, 323–331.
Scholthof, H. B., Scholthof, K.-B.G, Kikkert, M., and Jackson, A. O. (1995). Tomato bushy stunt virus spread is regulated by two nested genes that function in cell-to-cell movement and host-dependent systemic invasion. Virology 213, 425–438.
Shintaku, M. H. (1991). Coat protein gene sequence of two cucumber mosaic virus strains reveal a single amino acid change correlating with chlorosis induction. J. Gen. Virol. 72, 2587–2589.
Shintaku, M. H., and Palukaitis, P. (1990). Mapping determinants of pathogenicity and transmission of cucumber mosaic virus. Phatopathology 80. 1035.
Shintaku, M. H., Zhang, L., and Palukaitis, P. (1992). A single amino acid substitution in the coat protein of cucumber mosaic virus induces chlorosis in tobacco. Plant Cell 4, 751–757
Suzuki, M., Kuwata, S., Masuta, C., and Takanami, Y. (1995). Point mutations in the coat protein of cucumber mosaic virus affect symptom expression and virion accumulation in tobacco. J Gen. Virol. 76, 1791–1799.
Traynor, P., Young, B. M., and Ahlquist, P. (1991). Deletion analysis of brome mosaic virus 2a protein: Effects on RNA replication and systemic spread. J. Virol. 65, 2807–2815.
Tsai, C.-H., and Dreher, T. W. (1993). Increased viral yield and symptom severity result from a single amino acid substitution in the turnip yellow mosaic virus movement protein. Mot. Plant-Microbe Interact. 6, 268–273
van der Vossen, E. A. G., Neeleman, L., and Bol, J. F. (1994). Early and late functions of alfalfa mosaic virus coat protein can be mutated separately. Virology 202, 891–903.
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1999 Springer Science+Business Media New York
About this chapter
Cite this chapter
Rao, A.L.N. (1999). Molecular Basis of Symptomatology. In: Mandahar, C.L. (eds) Molecular Biology of Plant Viruses. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-5063-1_9
Download citation
DOI: https://doi.org/10.1007/978-1-4615-5063-1_9
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4613-7302-5
Online ISBN: 978-1-4615-5063-1
eBook Packages: Springer Book Archive