Abstract
UV-light as an important part of natural light spectra receives growing interest. UV-light of different wavelenghts interacts with different molecular structures. UVB (280-320nm) is mainly absorbed by aminoacids with conjugated dopplebonds and DNA. The corresponding energy transfer is high enough to break up covalent bonds. UVA (320-400nm) excites mainly delocalized p-electrons, which transmit this energy to oxygen, creating reactive oxygen species (ROS). Both mechanisms shift the equilibrium of redox pairs in tissue towards oxidation. Oxidative stress occurs, when the oxidative influences overwhelm the antioxidative acting substances. This antioxidant system consists of enzymes and a nonenzymatic part. Substances like hydrophil glutathione (GSH) and lipophil α-tocoferole (Vit E) stabilize the homeostasis of redox potential. Enzymes like superoxide dismutase (SOD), gluthatione peroxidase (GPX), glutathione reductase (GR), and glutathioneS-transferase (GST) are directly or indirectly involved in neutralizing ROS.
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Roeckl, T. et al. (1999). UV-Irradiation Affects Antioxidants in the Intravascular Compartment. In: Holick, M.F., Jung, E.G. (eds) Biologic Effects of Light 1998. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-5051-8_8
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DOI: https://doi.org/10.1007/978-1-4615-5051-8_8
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