Abstract
The association of neutropenia and infection in patients with cancer receiving myelosuppressive chemotherapy was established over three decades ago by Bodey et al, who demonstrated that the risk of infection began to increase as the neutrophil count fell below 1000/mm3 and was greatest at levels below 100/mm3 (Figure 1)1.
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Rubenstein, E.B., Elting, L.S., Sun, C.C., Rolston, K.V.I. (1999). Outpatient Management of Neutropenic Fever: Antibiotics, Growth Factors or Both?. In: Wingard, J.R., Demetri, G.D. (eds) Clinical Applications of Cytokines and Growth Factors. Developments in Oncology, vol 80. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-5013-6_8
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