Abstract
Prevention of coronary heart disease is not only important from the public health point of view. Efforts to prevent disease test our fundamental concepts of etiology. Atherosclerotic coronary heart disease is a complex process of atherosclerotic plaque accumulation and interaction with a thrombotic and fibrinolytic system, which may or may not ultimately result in a clinical syndrome. Because of the slowness and complexity of this lifelong process, preventive interventions may as well seem too weak or too slow in their power to appreciably alter the course of clinical disease. The societal burden of this disease, however, has become so great and its treatment so technologically complex, that even small gains in its prevention applied to large populations can be appreciable in terms of both reduction in human suffering and reduction in health care expenditures.
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Smith, D.A. (1999). Lipid Lowering Therapy. In: Contemporary Concepts in Cardiology. Developments in Cardiovascular Medicine, vol 217. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-5007-5_4
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DOI: https://doi.org/10.1007/978-1-4615-5007-5_4
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