Abstract
Although balloon angioplasty has been a significant advance in the treatment of patients with coronary artery disease, this treatment is limited by a significant incidence of restenosis that averages about 50% in most recent reports.1,2,3 Restenosis after balloon angioplasty is associated with the healing response of vascular tissue to injury and involves platelet deposition, inflammatory cell infiltration, smooth muscle cell proliferation, and extracellular matrix formation.4 Because the mechanism of vessel dilatation in balloon angioplasty involves significant vessel injury with intimal fissuring, limited penetration into the subintimal space, and occasionally deep dissection into the media, it was hoped that interventional methods causing less vascular injury would decrease the likelihood of restenosis.
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Ting, H.H., Timimi, F.K., Bittl, J.A. (1999). Excimer Laser Angioplasty. In: Contemporary Concepts in Cardiology. Developments in Cardiovascular Medicine, vol 217. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-5007-5_29
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DOI: https://doi.org/10.1007/978-1-4615-5007-5_29
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