Abstract
The clinical states of non-insulin dependent diabetes mellitus (NIDDM), essential hypertension, and cardiovascular disease are major causes of morbidity and mortality in the United States. The prevalence of NIDDM in the U.S. currently approaches 5 to 7 percent.1 In 1992 this resulted in a cost to the health care system of approximately $45 billion.2 On a similar scale, cardiovascular disease contributes to approximately 900,000 deaths per year in the United States, nearly 40 percent of deaths due to all causes.3 Furthermore, essential hypertension is perhaps the most prevalent cardiovascular disease affecting an estimated 50 million Americans.3
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Slogoff, F.B., Wasserman, E.J., Phillips, R.A. (1999). Insulin Resistance, and Hypertension. In: Contemporary Concepts in Cardiology. Developments in Cardiovascular Medicine, vol 217. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-5007-5_10
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