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Complementing The Cell: Glycoform Synthesis In Vitro

  • Chapter
Protein Glycosylation

Abstract

One of the many challenges in the field of glycobiology is the isolation of the pure glycoforms of a glycoprotein since the study of these glycoforms, or their synthetic analogues, is likely to provide a unique insight into the very nature of the glycoprotein itself. In particular, since glycoforms contain a well-defined oligosaccharide side chain at each glycosylation site, they are invaluable tools in understanding the relationship between oligosaccharide sequence and glycoprotein function: one of the holy grails of biology.

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Authors and Affiliations

  1. The Lundberg Laboratory, University of Göteborg, Box 462, S-405 30, Göteborg, Sweden

    Roslyn M. Bill M.A., D.Phil., M.R.S.C., C.Chem.

  2. Department of Biochemistry Research, The Hospital for Sick Children, 555 University Avenue, Toronto, Ontario, M5G 1X8, Canada

    Leigh Revers M.A., D.Phil.

  3. Department of Biochemistry Research, University of Dundee, The Wellcome Trust Building, Dow Street, Dundee, DD1 5EH, Scotland

    Iain B. H. Wilson B.Sc.(Hons), D.Phil., M.R.S.C., C.Chem.

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  1. Roslyn M. Bill M.A., D.Phil., M.R.S.C., C.Chem.
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  2. Leigh Revers M.A., D.Phil.
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  3. Iain B. H. Wilson B.Sc.(Hons), D.Phil., M.R.S.C., C.Chem.
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© 1998 Springer Science+Business Media New York

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Bill, R.M., Revers, L., Wilson, I.B.H. (1998). Complementing The Cell: Glycoform Synthesis In Vitro. In: Protein Glycosylation. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-4939-0_9

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  • DOI: https://doi.org/10.1007/978-1-4615-4939-0_9

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