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Stress Effects on Immune Function in Rodents

  • Melissa K. Demetrikopoulos
  • Steven E. Keller
  • Steven J. Schleifer

Abstract

There is a vast literature examining the effects of stress on immune function in rodents. This chapter will provide an overview of this literature by describing the immunological changes that occur in response to stress and the mechanisms by which these changes are believed to occur. It begins with a description of various rodent models used to study stress effects of immunity to provide an appreciation for the types and breadth of experiments likely to be performed in this field. This is followed by more specific examples of stress-induced immunological changes. The final section of the chapter explores neuronal mechanisms by which this occurs.

Keywords

Natural Killer Stress Effect Natural Killer Activity Hypothalamic Lesion Shock Stress 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1999

Authors and Affiliations

  • Melissa K. Demetrikopoulos
    • 1
  • Steven E. Keller
    • 2
  • Steven J. Schleifer
    • 3
  1. 1.Institute for Biomedical PhilosophyChambleeUSA
  2. 2.Department of Psychiatry and NeuroscienceUMDNJ New Jersey Medical SchoolNewarkUSA
  3. 3.Department of PsychiatryUMDNJ New Jersey Medical SchoolNewarkUSA

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