Sickness Behavior

A Neuroimmune-Based Response to Infectious Disease
  • Robert Dantzer


Nonspecific symptoms of infection and inflammation include fever and profound physiological and behavioral changes. Sick individuals experience weakness, malaise, listlessness, and inability to concentrate. They become depressed and lethargic, show little interest in their surroundings, and stop eating and drinking. This constellation of non-specific symptoms is collectively referred to as sickness behavior. Because of their commonality, sickness symptoms are frequently ignored by physicians. They are often considered as an uncomfortable, but rather banal, component of the pathogen-induced debilitative process.


Behavioral Effect Chronic Fatigue Syndrome Vagus Nerve Depressing Effect Conditioned Taste Aversion 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media New York 1999

Authors and Affiliations

  • Robert Dantzer
    • 1
  1. 1.INSERM U394Bordeaux CedexFrance

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