Abstract
The liver is central to copper metabolism in mammals. Following transfer across the gut, about 40 % of the metal is taken up from the portal vein in each pass (see (Linder, 1991)). The liver also excretes Cu through the bile. The chemical characteristics of Cu in bile are poorly understood, but it is probably excreted as a Cu ion and complexes with bile salt in the canaliculi.
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McArdle, H.J., Bingham, M.J., Summer, K., Ong, T.J. (1999). Cu Metabolism in the Liver. In: Leone, A., Mercer, J.F.B. (eds) Copper Transport and Its Disorders. Advances in Experimental Medicine and Biology, vol 448. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-4859-1_3
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DOI: https://doi.org/10.1007/978-1-4615-4859-1_3
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