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The Effect of Copper on Tight Junctional Permeability in a Human Intestinal Cell Line (Caco-2)

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Copper Transport and Its Disorders

Abstract

Copper is a trace element essential to life, participating to a wide number of biochemical reactions as cofactor of many enzymes (Linder, 1991). However, it also exhibits toxic effects and can impair cellular functions (Goyer, 1994). For this reason it is crucial to understand the relashionship between requirements and toxicity of this heavy metal.

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© 1999 Springer Science+Business Media New York

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Ferruzza, S., Sambuy, Y., Rotilio, G., Ciriolo, M.R., Scarino, M.L. (1999). The Effect of Copper on Tight Junctional Permeability in a Human Intestinal Cell Line (Caco-2). In: Leone, A., Mercer, J.F.B. (eds) Copper Transport and Its Disorders. Advances in Experimental Medicine and Biology, vol 448. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-4859-1_19

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  • DOI: https://doi.org/10.1007/978-1-4615-4859-1_19

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-7204-2

  • Online ISBN: 978-1-4615-4859-1

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