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Prevalence of IgM-, IgA- and IgG-Rheumatoid Factors in Seronegative Polyarticular Disease Compared to Pauciarticular Disease in Juvenile Chronic Arthritis as Measured by Elisa

  • Boriana B. Varbanova
  • M. Baleva
  • K. Nikolov
  • D. Mihailova
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 455)


To determine the prevalence of the rheumatoid factor isotypes measured by enzyme- linked immunosorbent assay (ELISA) in polyarticular and pauciarticular juvenile chronic arthritis (JCA), and evaluate the diagnostic test qualities.


Rheumatoid Factor Familial Mediterranian Fever Juvenile Rheumatoid Arthritis Juvenile Chronic Arthritis Juvenile Arthritis 
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Copyright information

© Springer Science+Business Media New York 1999

Authors and Affiliations

  • Boriana B. Varbanova
    • 1
  • M. Baleva
    • 2
  • K. Nikolov
    • 3
  • D. Mihailova
    • 4
  1. 1.Department of PaediatricsVarna Medical UniversityBulgaria
  2. 2.Laboratory of Clinical ImmunologyNational Centre of AllergologyUSA
  3. 3.Department of DermatologyLaboratory of Clinical ImmunologyUSA
  4. 4.Department of PaediatricsMedical University of SofiaBulgaria

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