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Pyoderma Gangrenosum Successfully Treated with Cyclosporin A

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Rheumaderm

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 455))

Abstract

The subjects of the study are a 48-year old male and a 50-year female patient with the idiopathic form of pyoderma gangrenosum. Both patients were treated with Cyclosporin A (Sandimmun) as monotherapy. Complete resolution was achieved after three months’ treatment. No serious side-effects were observed.

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References

  1. Brunsting LA, Goeckerman WH, O’Leary PA. Pyoderma (ecthyma) gangrenosum: Clinical and experimental observations in five cases occuring in adults. Arch Dermatol 22:655–680 (1930)

    Article  Google Scholar 

  2. Jones RR: Cutaneous manifestations of paraproteinemia. Br J Dermatol. 104:209–220 (1981)

    Article  PubMed  CAS  Google Scholar 

  3. Borel JF. In: Kahan B, ed. Cyclosporine:Nature of the Agent and its Immunologic Actions. New York, NY:Guine and Stratton 722–730 (1988)

    Google Scholar 

  4. Furue M, Gaspari A, Katz S. The effect of cyclosporin A on epidermal cells II: cyclosporin A inhibits proliferation of normal and transformed keratinocytes. J Invest Dermatol 90:796–800 (1988).

    Article  PubMed  CAS  Google Scholar 

  5. Elgart G, Larson K, Stover P, Davis B. Effective treatment of pyoderma gangrenosum with cyclosporin: a report of five cases. J Invest Dermatol. 92:424 (1989)

    Google Scholar 

  6. Magid ML, Gold MH. Treatment of recalcitrant pyoderma gangrenosum with cyclosporine. J Am Acad Dermatol. 20:293–294 (1989).

    Article  PubMed  CAS  Google Scholar 

  7. Curley RK, Mcfarlane AW, Vickers CFH. Pyoderma Gangrenosum treated with Cyclosporine. Br J Dermatol. 113:601–604(1985).

    Article  PubMed  CAS  Google Scholar 

  8. Ho VC, Dutz J, Gulliver W, Lauzon G. Canadian experience of cyclosporin A (Sandimmun and Sandimmun Neoral) in the treatment of refractory pyoderma gangrenosum. International Congress on Immunointervention. The Role of Neoral in Immune-Based Diseases. Rome, Italy, June 1996 (Abstracts)

    Google Scholar 

  9. Mork NJ, Mork G, Koss-Harnes D. Severe pyoderma gangrenosum successfully treated with cyclosporin. International Congress on Immunointervention. The Role of Neoral in Immune-Based Diseases. Rome, Italy, June 1996 (Abstracts)

    Google Scholar 

  10. Wang DZ, McCafrey PG, Rao A. The Cyclosporin-sensitive transcription factor NFATp is expressed in several classes of cells in the immune system. Ann New York Acad Sci 766:182–194 (1995)

    Article  CAS  Google Scholar 

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Author information

Authors and Affiliations

  1. Department of Dermatology, University of Skopje, USA

    Prof. M. T. V’lčkova-Laskoska, D. S. Laskoski, N. G. Caca-Biljanovska & J. S. Darkoska

Authors
  1. Prof. M. T. V’lčkova-Laskoska
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  2. D. S. Laskoski
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  3. N. G. Caca-Biljanovska
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  4. J. S. Darkoska
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Corresponding author

Correspondence to M. T. V’lčkova-Laskoska .

Editor information

Editors and Affiliations

  1. St. Luke’s Hospital, University of Malta Medical School, Malta, USA

    Carmel Mallia

  2. Jefferson Medical College, Thomas Jefferson Universit, Philadelphia, Pennsylvania, USA

    Jouni Uitto

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© 1999 Springer Science+Business Media New York

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V’lčkova-Laskoska, M.T., Laskoski, D.S., Caca-Biljanovska, N.G., Darkoska, J.S. (1999). Pyoderma Gangrenosum Successfully Treated with Cyclosporin A. In: Mallia, C., Uitto, J. (eds) Rheumaderm. Advances in Experimental Medicine and Biology, vol 455. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-4857-7_81

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  • DOI: https://doi.org/10.1007/978-1-4615-4857-7_81

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-7203-5

  • Online ISBN: 978-1-4615-4857-7

  • eBook Packages: Springer Book Archive

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