Rheumaderm pp 23-26 | Cite as

Neonatal Lupus Erythematosus

  • B. R. Krafchik
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 455)


Neonatal lupus is categorized by typical clinical features and the presence of maternal auto-antibodies. Mothers are uncommonly affected with clinical disease. The major clinical manifestations in neonates are cardiac, dermatological and hepatic, with rare instances of haemolytic anaemia and thrombocytopenia. The major morbidity and mortality result from complete congenital heart block. Dermatological manifestations occur mainly over the face and present with plaques of erythema with central atrophy, a mid-facial erythema, atrophy around the eyes and a telangiectatic variety. The long term outcome is usually excellent.


Systemic Lupus Erythematosus Patent Ductus Arteriosus Complete Heart Block Cutaneous Lupus Erythematosus Congenital Heart Block 
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Copyright information

© Springer Science+Business Media New York 1999

Authors and Affiliations

  • B. R. Krafchik
    • 1
  1. 1.Department of DermatologyHospital for Sick ChildrenTorontoCanada

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