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Neonatal Lupus Erythematosus

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Rheumaderm

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 455))

Abstract

Neonatal lupus is categorized by typical clinical features and the presence of maternal auto-antibodies. Mothers are uncommonly affected with clinical disease. The major clinical manifestations in neonates are cardiac, dermatological and hepatic, with rare instances of haemolytic anaemia and thrombocytopenia. The major morbidity and mortality result from complete congenital heart block. Dermatological manifestations occur mainly over the face and present with plaques of erythema with central atrophy, a mid-facial erythema, atrophy around the eyes and a telangiectatic variety. The long term outcome is usually excellent.

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© 1999 Springer Science+Business Media New York

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Krafchik, B.R. (1999). Neonatal Lupus Erythematosus. In: Mallia, C., Uitto, J. (eds) Rheumaderm. Advances in Experimental Medicine and Biology, vol 455. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-4857-7_4

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  • DOI: https://doi.org/10.1007/978-1-4615-4857-7_4

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-7203-5

  • Online ISBN: 978-1-4615-4857-7

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