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Rheumaderm pp 227–233Cite as

Pyridinium Crosslinks Excretion in Patients with Rheumatoid Arthritis

Correlation with Disease Activity and Glucocorticoid Treatment

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Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 455))

Summary

In patients with rheumatoid arthritis, significant positive correlations were found between urinary pyridinium crosslinks and C-reactive protein (CRJP), erythrocyte sedimentation rate (ESR) and articular index. Also an inverse correlation was observed between pyridinium crosslinks excretion and grip strength. Glucocorticoid therapy, equivalent to daily doses of 7.5mg of prednisolone or less, did not appear to have deleterious effect on bone metabolism in these patients as measured by urinary pyridinium crosslinks.

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Authors and Affiliations

  1. Department of Medicine, University of Malta Medical School, Guardamangia, Malta, USA

    F. Camilleri & Dr. Carmel Mallia (Chairman)

  2. Department of Pathology, University of Malta Medical School, Guardamangia, Malta, USA

    A. Xuereb Anastasi & M. Cauchi

  3. University of Malta Statistics Unit, Msida, Malta, USA

    A. Buhagiar

Authors
  1. A. Xuereb Anastasi
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  2. A. Buhagiar
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  3. F. Camilleri
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  4. M. Cauchi
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  5. Dr. Carmel Mallia
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Corresponding author

Correspondence to Carmel Mallia .

Editor information

Editors and Affiliations

  1. St. Luke’s Hospital, University of Malta Medical School, Malta, USA

    Carmel Mallia

  2. Jefferson Medical College, Thomas Jefferson Universit, Philadelphia, Pennsylvania, USA

    Jouni Uitto

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© 1999 Springer Science+Business Media New York

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Anastasi, A.X., Buhagiar, A., Camilleri, F., Cauchi, M., Mallia, C. (1999). Pyridinium Crosslinks Excretion in Patients with Rheumatoid Arthritis. In: Mallia, C., Uitto, J. (eds) Rheumaderm. Advances in Experimental Medicine and Biology, vol 455. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-4857-7_33

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  • DOI: https://doi.org/10.1007/978-1-4615-4857-7_33

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-7203-5

  • Online ISBN: 978-1-4615-4857-7

  • eBook Packages: Springer Book Archive

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