Abstract
It is of great interest, though somewhat puzzling, that nitric oxide (NO) can play simultaneously the dual role of messenger (Moncada et al., 1991), and inhibitor (Bredt and Snider, 1994; Nathan, 1992). The balance between these two functions will depend on a number of parameters, ranging from the cell-tissues pathophysiological state to the relative concentration in vivo of O2 and NO.
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Giuffrè, A., Sarti, P., D’Itri, E., Buse, G., Soulimane, T., Brunori, M. (1999). Transient Spectroscopy of the Reaction between Cytochrome c Oxidase and Nitric Oxide. In: Papa, S., Guerrieri, F., Tager, J.M. (eds) Frontiers of Cellular Bioenergetics. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-4843-0_10
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DOI: https://doi.org/10.1007/978-1-4615-4843-0_10
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