Prodigiosins — A New Family of Immunosuppressants Novel and Efficient Synthesis

Abstract

Prodigiosins (Ps) are a class of naturally occurring red pigments produced by Streptomyces Genus and characterised by a peculiar 2,2’-bipyrrolyl-pyrromethene skeleton (Figure 1). Prodigiosin, the first isolated member¹ , has been shown to possess potent antimicrobial and cytotoxic properties. It was never used in therapy because of high systemic toxicity.